Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.39 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.39 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.39 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.39 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.38 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.38 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.38 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 6/20 | 0.38 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13909446 | 1.00 | ALDH1A1 (0.42) | ALDH1A1KDM4EGAAHPGDPDK1 | |
| SCHEMBL13909445 | 0.95 | PDK1 (0.41) | ALDH1A1KDM4EGAAHPGDPDK1 | |
| SCHEMBL4181415 | 0.95 | PDK1 (0.41) | ALDH1A1KDM4EGAAHPGDPDK1 | |
| SCHEMBL13909450 | 0.90 | MAPT (0.41) | ALDH1A1KDM4EPDK1PDK2PDK3 | |
| SCHEMBL4176199 | 0.90 | MAPT (0.41) | ALDH1A1KDM4EPDK1PDK2PDK3 | |
| SCHEMBL4168242 | 0.89 | KDM4E (0.42) | ALDH1A1KDM4EGAAHPGDPDK1 | |
| SCHEMBL13909448 | 0.89 | KDM4E (0.42) | ALDH1A1KDM4EGAAHPGDPDK1 | |
| SCHEMBL4170954 | 0.84 | ABCB1 (0.39) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL13909454 | 0.84 | ABCB1 (0.39) | ALDH1A1KDM4EHPGDSMN1; SMN2KMT2A | |
| SCHEMBL13909245 | 0.81 | AR (0.52) | ALDH1A1GAAARLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090075989-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AG (DE) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090075989-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | NR5A1, CYP19A1, GPER1 | ALDH1A1 695/4885KDM4E 1525/4885GAA 4824/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.