Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13909454 | 1.00 | ABCB1 (0.39) | ABCB1RAB9ACTSLNR3C2KDM4E | |
| SCHEMBL4176199 | 0.90 | MAPT (0.41) | RAB9AKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL13909450 | 0.90 | MAPT (0.41) | RAB9AKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL13909448 | 0.89 | KDM4E (0.42) | CTSLNR3C2KDM4EMEN1KMT2A | |
| SCHEMBL4168242 | 0.89 | KDM4E (0.42) | CTSLNR3C2KDM4EMEN1KMT2A | |
| SCHEMBL4181415 | 0.88 | PDK1 (0.41) | NR3C2KDM4EALDH1A1HPGD | |
| SCHEMBL13909445 | 0.88 | PDK1 (0.41) | NR3C2KDM4EALDH1A1HPGD | |
| SCHEMBL4159577 | 0.84 | ALDH1A1 (0.42) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL13909446 | 0.84 | ALDH1A1 (0.42) | KDM4EMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4180793 | 0.83 | AR (0.48) | KDM4EALDH1A1MAPTUSP2HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090075989-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | BAYER SCHERING PHARMA AG (DE) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090075989-A1 | NON-STEROIDAL PROGESTERONE RECEPTOR MODULATORS | NR5A1, CYP19A1, GPER1 | ABCB1 903/4885RAB9A 4606/4885CTSL 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.