SCHEMBL4160169

SCHEMBL4160169

CCCCCCc1cc2c(cc1O)Oc1cc(O)c(Cl)cc1C21OC(=O)c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.48
MEN1 O00255 8/20 0.48
KMT2A Q03164 8/20 0.48
HTT P42858 5/20 0.48
TDP1 Q9NUW8 4/20 0.48
CYP2C19 P33261 3/20 0.48
RECQL P46063 3/20 0.48
BLM P54132 3/20 0.48
FTO Q9C0B1 2/20 0.48
PRMT1 Q99873 2/20 0.48
ACE2 Q9BYF1 2/20 0.48
HPGD P15428 2/20 0.48
SMAD3 P84022 1/20 0.48
CYP3A4 P08684 2/20 0.46
LMNA P02545 5/20 0.45
USP2 O75604 4/20 0.45
ALDH1A1 P00352 3/20 0.45
NPSR1 Q6W5P4 5/20 0.41
POLB P06746 4/20 0.41
GNG2 P59768 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10176074 0.85 MAPT (0.54) MAPTMEN1KMT2AHTTTDP1
SCHEMBL4941419 0.85 MAPT (0.59) MAPTMEN1KMT2AHTTTDP1
Dichlorofluorescein SCHEMBL29364373 0.85 MAPT (0.64) MAPTMEN1KMT2AHTTTDP1
Dichlorofluorescein SCHEMBL157703 0.85 MAPT (0.64) MAPTMEN1KMT2AHTTTDP1
Dichlorofluorescein SCHEMBL30606648 0.85 MAPT (0.64) MAPTMEN1KMT2AHTTTDP1
Dichlorofluorescein SCHEMBL25207800 0.84 MAPT (0.63) MAPTMEN1KMT2AHTTTDP1
SCHEMBL14137639 0.84 MAPT (0.42) MAPTMEN1KMT2AHTTTDP1
Dichlorofluorescein SCHEMBL21196869 0.82 MAPT (0.57) MAPTMEN1KMT2AHTTTDP1
SCHEMBL4933751 0.81 MAPT (0.63) MAPTMEN1KMT2AHTTTDP1
SCHEMBL15801068 0.81 MAPT (0.56) MAPTMEN1KMT2AHTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090004751-A1 Dry optical-chemical carbon-dioxide sensor ROCHE DIAGNOSTICS OPERATIONS, INC. (US) 2009-01-01 US disclosed
EP-1972929-A1 Dry optical - chemical carbon - dioxide sensor F. Hoffmann-Roche AG (CH) 2008-09-24 EP disclosed
EP-1965198-A1 Dry optical-chemical carbon-dioxide sensor F. Hoffmann-La Roche AG (CH) 2008-09-03 EP disclosed