Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11256962 | 0.76 | ALDH1A1 (0.46) | ALDH1A1TDP1L3MBTL1MAPK1KMT2A | |
| SCHEMBL9391305 | 0.75 | ALDH1A1 (0.45) | ALDH1A1TDP1L3MBTL1MAPK1KMT2A | |
| SCHEMBL11233359 | 0.75 | ALDH1A1 (0.45) | ALDH1A1TDP1L3MBTL1MAPK1KMT2A | |
| Cyclohexanone SCHEMBL2854193 | 0.73 | CYP3A4 (0.54) | ALDH1A1TDP1L3MBTL1MAPK1KMT2A | |
| SCHEMBL6558775 | 0.73 | CYP3A4 (0.44) | ALDH1A1TDP1L3MBTL1MAPK1KMT2A | |
| SCHEMBL4167580 | 0.72 | ALDH1A1 (0.49) | ALDH1A1TDP1L3MBTL1MAPK1KMT2A | |
| SCHEMBL9785319 | 0.72 | ALDH1A1 (0.49) | ALDH1A1TDP1L3MBTL1MAPK1KMT2A | |
| SCHEMBL15987361 | 0.72 | CYP2C19 (0.49) | ALDH1A1TDP1L3MBTL1MAPK1KMT2A | |
| SCHEMBL1128419 | 0.71 | ALDH1A1 (0.47) | ALDH1A1TDP1L3MBTL1MAPK1KMT2A | |
| SCHEMBL61861 | 0.71 | KMT2A (0.66) | ALDH1A1L3MBTL1KMT2ACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069287-A1 | SUBSTITUTED AZACYCLOALKANES USEFUL FOR TREATING CNS CONDITIONS | PFIZER INC | 2009-03-12 | — | — | US | disclosed |
| EP-1957448-A1 | SUBSTITUTED AZACYCLOALKANES USEFUL FOR TREATING CNS CONDITIONS | Pfizer Products Inc. (US) | 2008-08-20 | — | — | EP | disclosed |
| WO-2007060526-A1 | SUBSTITUTED AZACYCLOALKANES USEFUL FOR TREATING CNS CONDITIONS | PFIZER PRODUCTS INC. (US) | 2007-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069287-A1 | SUBSTITUTED AZACYCLOALKANES USEFUL FOR TREATING CNS CONDITIONS | BACE2, BACE1, PMP22 | ALDH1A1 1601/4885TDP1 586/4885L3MBTL1 4208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.