Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.65 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.65 |
| ▸ | POLB | P06746 | 3/20 | 0.65 |
| ▸ | APEX1 | P27695 | 3/20 | 0.65 |
| ▸ | RECQL | P46063 | 3/20 | 0.65 |
| ▸ | APP | P05067 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | MPG | P29372 | 2/20 | 0.65 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | BLM | P54132 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | YES1 | P07947 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30627918 | 0.88 | CYP3A4 (0.75) | CYP3A4KDM4EABCG2POLBAPEX1 | |
| SCHEMBL4160544 | 0.88 | CYP3A4 (0.75) | CYP3A4KDM4EABCG2POLBAPEX1 | |
| SCHEMBL30627917 | 0.88 | CYP3A4 (0.75) | CYP3A4KDM4EABCG2POLBAPEX1 | |
| SCHEMBL4170658 | 0.87 | KDM4E (0.61) | CYP3A4KDM4EABCG2POLBAPEX1 | |
| SCHEMBL4166913 | 0.85 | KDM4E (0.58) | CYP3A4KDM4EABCG2POLBAPEX1 | |
| SCHEMBL4157325 | 0.84 | ABCB1 (0.76) | CYP3A4KDM4EABCG2POLBAPEX1 | |
| SCHEMBL4163598 | 0.84 | KDM4E (0.47) | CYP3A4KDM4EABCG2POLBAPEX1 | |
| SCHEMBL31236662 | 0.83 | POLH (0.76) | CYP3A4KDM4EABCG2POLBAPEX1 | |
| SCHEMBL4175201 | 0.83 | POLH (0.76) | CYP3A4KDM4EABCG2POLBAPEX1 | |
| SCHEMBL4155155 | 0.82 | KDM4E (0.55) | CYP3A4KDM4EABCG2POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 2009-05-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | CAT, NQO1, GPX4 | CYP3A4 518/4885KDM4E 4144/4885ABCG2 102/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.