Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.45 |
| ▸ | APEX1 | P27695 | 3/20 | 0.45 |
| ▸ | RECQL | P46063 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MPG | P29372 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4156024 | 0.87 | ADORA3 (0.56) | KDM4EMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL4161561 | 0.84 | CYP3A4 (0.65) | KDM4EMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL4168940 | 0.79 | ADORA3 (0.42) | KDM4EMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL4173907 | 0.79 | CYP3A4 (0.54) | KDM4EMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL4175448 | 0.78 | ADORA3 (0.41) | KDM4EMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL4157882 | 0.76 | HTT (0.40) | KDM4EMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL4153248 | 0.75 | ALOX5 (0.41) | KDM4EMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL4161249 | 0.75 | ALOX5 (0.41) | KDM4EMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL4162126 | 0.75 | ALOX5 (0.41) | KDM4EMEN1KMT2ACYP3A4ALDH1A1 | |
| SCHEMBL4164234 | 0.75 | ALOX5 (0.41) | KDM4EMEN1KMT2ACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | HOWARD FLOREY INSTITUTE OF EXPERIMENTAL PHYSIOLOGY AND MEDICINE (AU) | 2009-05-21 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090130051-A1 | Flavonoid Compounds and Uses Thereof | CAT, NQO1, GPX4 | KDM4E 4144/4885MEN1 4830/4885KMT2A 4797/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.