Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I3 | Q14994 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4161721 | 0.99 | CYP1A2 (0.49) | NR1I3KCNH2TMEM97SIGMAR1CYP1A2 | |
| SCHEMBL3243483 | 0.91 | NR1I3 (0.56) | NR1I3KCNH2TMEM97SIGMAR1CYP1A2 | |
| Hydrochloric Acid SCHEMBL3950184 | 0.90 | CYP1A2 (0.58) | NR1I3KCNH2TMEM97SIGMAR1CYP1A2 | |
| SCHEMBL9618249 | 0.85 | CYP1A2 (0.61) | SIGMAR1CYP1A2CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL12521058 | 0.84 | CHRM2 (0.57) | KCNH2TMEM97SIGMAR1CYP1A2CYP2C19 | |
| SCHEMBL12520868 | 0.83 | CHRM2 (0.57) | SIGMAR1CYP1A2CYP2D6CYP2C19HDAC3 | |
| SCHEMBL3237536 | 0.79 | SIGMAR1 (0.64) | SIGMAR1CA1CA2HDAC3HDAC4 | |
| SCHEMBL3276787 | 0.79 | CA1 (0.51) | NR1I3KCNH2TMEM97SIGMAR1CYP1A2 | |
| SCHEMBL5177620 | 0.79 | CYP1A2 (0.52) | NR1I3KCNH2TMEM97SIGMAR1CYP1A2 | |
| SCHEMBL3947879 | 0.79 | CA1 (0.51) | NR1I3KCNH2TMEM97SIGMAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090171091-A1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CADILA HEALTHCARE LIMITED (IN) | 2009-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090171091-A1 | COMPOUNDS SUITABLE AS MODULATORS OF HDL | CETP, APOB, HDLBP | NR1I3 110/4885KCNH2 4719/4885TMEM97 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.