SCHEMBL9618249

SCHEMBL9618249

Clc1ccc(CCCNCc2ccc(Cl)c(Cl)c2)cc1Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.61
CYP2D6 P10635 1/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
SIGMAR1 Q99720 6/20 0.59
ALOX15 P16050 2/20 0.51
IGF1R P08069 1/20 0.51
ROCK1 Q13464 1/20 0.51
PNMT P11086 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
MARS1 P56192 1/20 0.48
PYGL P06737 1/20 0.47
CHRM2 P08172 2/20 0.47
TRPV1 Q8NER1 1/20 0.47
PRMT5 O14744 1/20 0.46
WDR77 Q9BQA1 1/20 0.46
PLA2G1B P04054 1/20 0.45
POLB P06746 1/20 0.45
ATG4B Q9Y4P1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6076785 0.90 SIGMAR1 (0.63) CYP1A2CYP2D6CYP2C9CYP2C19SIGMAR1
SCHEMBL11089154 0.86 CYP1A2 (0.66) CYP1A2CYP2D6CYP2C9CYP2C19SIGMAR1
SCHEMBL4162397 0.85 NR1I3 (0.49) CYP1A2CYP2D6CYP2C9CYP2C19SIGMAR1
SCHEMBL7805399 0.84 POLB (0.55) CYP1A2CYP2D6CYP2C9CYP2C19SIGMAR1
SCHEMBL7805116 0.84 SIGMAR1 (0.62) CYP1A2CYP2D6CYP2C9CYP2C19SIGMAR1
SCHEMBL14058901 0.84 SMN1; SMN2 (0.59) CYP1A2CYP2D6CYP2C9CYP2C19SIGMAR1
Hydrochloric Acid SCHEMBL4161721 0.83 CYP1A2 (0.49) CYP1A2CYP2D6CYP2C9CYP2C19SIGMAR1
SCHEMBL7263108 0.83 SIGMAR1 (0.71) CYP1A2CYP2D6CYP2C9CYP2C19SIGMAR1
SCHEMBL10070258 0.82 CYP1A2 (0.54) CYP1A2CYP2D6CYP2C9CYP2C19SIGMAR1
SCHEMBL8092923 0.82 SIGMAR1 (0.66) SIGMAR1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-4321647-A None JP disclosed
JP-H04321647-A DICHLOROPHENYLPROPYLAMINE AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE MITSUBISHI GAS CHEM CO INC 1992-11-11 JP disclosed