Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN7 | P35236 | 1/20 | 0.54 |
| ▸ | PDE2A | O00408 | 2/20 | 0.53 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.53 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.53 |
| ▸ | MIF | P14174 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | IAPP | P10997 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4176477 | 0.84 | SCN9A (0.44) | PDE3BPDE3AP2RY12KDM4EALDH1A1 | |
| SCHEMBL21865487 | 0.83 | MEN1 (0.57) | KDM4EMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL7342388 | 0.83 | HDAC8 (0.55) | KDM4EALDH1A1MAPTNCF1 | |
| SCHEMBL2905942 | 0.82 | PDE2A (0.45) | PTPN7PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL8184522 | 0.79 | PTPN7 (0.61) | PTPN7KDM4EMEN1KMT2ATDP1 | |
| SCHEMBL16880740 | 0.78 | HSD17B14 (0.51) | KDM4EMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL2903172 | 0.78 | PTPN7 (0.43) | PTPN7PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL23452954 | 0.77 | PTPN7 (0.52) | PTPN7PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL4076964 | 0.77 | PTPN7 (0.85) | PTPN7PDE2APDE3BPDE3AP2RY12 | |
| SCHEMBL21865489 | 0.77 | KDM4E (0.43) | KDM4EALDH1A1MAPTNCF1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090197914-A1 | Piperidine Derivatives, Their Process for Preparation, Their Use as Therapeutic Agents and Pharmaceutical Compositions Containing Them | ASTRAZENECA AB (SE) | 2009-08-06 | — | — | US | disclosed |
| EP-1994003-A1 | PIPERIDINE DERIVATIVES, THEIR PROCESS FOR PREPARATION, THEIR USE AS THERAPEUTIC AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM . | AstraZeneca AB (SE) | 2008-11-26 | — | — | EP | disclosed |
| WO-2007102768-A1 | PIPERIDINE DERIVATIVES, THEIR PROCESS FOR PREPARATION, THEIR USE AS THERAPEUTIC AGENTS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM . | ASTRAZENECA AB (SE) | 2007-09-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090197914-A1 | Piperidine Derivatives, Their Process for Preparation, Their Use as Therapeutic Agents and Pharmaceutical Compositions Containing Them | CCR3, CCR1, CCR4 | PTPN7 3707/4885PDE2A 174/4885PDE3B 61/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.