SCHEMBL268150

SCHEMBL268150

O=[N+]([O-])c1ccc(Sc2ccccc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.68
KMT2A Q03164 6/20 0.68
MAPT P10636 5/20 0.68
ALDH1A1 P00352 6/20 0.62
LMNA P02545 4/20 0.62
PDE7A Q13946 1/20 0.59
MAPK1 P28482 3/20 0.56
GAA P10253 1/20 0.56
PKM P14618 1/20 0.56
HPGD P15428 5/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
CRHBP P24387 1/20 0.53
ATM Q13315 1/20 0.53
CRHR2 Q13324 1/20 0.53
TLR9 Q9NR96 1/20 0.53
ALOX12 P18054 1/20 0.53
CES2 O00748 1/20 0.52
CES1 P23141 1/20 0.52
SMN1; SMN2 Q16637 4/20 0.51
HTT P42858 2/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3328543 0.91 MAPT (0.79) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL4163474 0.91 MAPT (0.79) MEN1KMT2AMAPTALDH1A1LMNA
Phosphonic Acid SCHEMBL11661426 0.91 MEN1 (0.58) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL8934655 0.89 MAPT (0.76) MEN1KMT2AMAPTALDH1A1LMNA
Fluoride SCHEMBL29135589 0.89 MAPT (0.76) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL8934649 0.89 MAPT (0.76) MEN1KMT2AMAPTALDH1A1LMNA
Diphenylsulfane SCHEMBL27732156 0.88 MEN1 (0.55) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL8729226 0.87 ALDH1A1 (0.62) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL11657737 0.85 AGTR1 (0.58) MEN1KMT2AMAPTALDH1A1LMNA
SCHEMBL2818369 0.84 MAPT (0.70) MEN1KMT2AMAPTALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120058570-A Application of metal ion doped graphene oxide film catalytic material in catalyzing thioether oxidation reaction to synthesize sulfone 中国科学院理化技术研究所 2025-05-30 CN claimed
US-7732534-B2 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION (JP) 2010-06-08 US claimed
US-20080051552-A1 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION 2008-02-28 US claimed
US-20080051519-A1 Polymers functionalized with nitro compounds BRIDGESTONE CORPORATION (JP) 2008-02-28 US claimed
US-4511729-A Nucleophilic substitution process ETHYL CORPORATION (US) 1985-04-16 US claimed
US-4502998-A Nucleophilic substitution process ETHYL CORPORATION (US) 1985-03-05 US claimed
CN-120058570-A Application of metal ion doped graphene oxide film catalytic material in catalyzing thioether oxidation reaction to synthesize sulfone 中国科学院理化技术研究所 2025-05-30 CN disclosed
CN-119528762-A Oxime oxalate compound, photoresist and application thereof 北京云基科技股份有限公司 2025-02-28 CN disclosed
US-11500247-B2 Liquid crystal sensor PLATYPUS TECHNOLOGIES, LLC (US) 2022-11-15 US disclosed
US-20210403456-A1 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY OTSUKA PHARMACEUTICAL CO., LTD. (JP) 2021-12-30 US disclosed
US-20200409221-A1 LIQUID CRYSTAL SENSOR PLATYPUS TECHNOLOGIES, LLC 2020-12-31 US disclosed
US-20170212088-A1 DETECTION OF GAS-PHASE ANALYTES USING LIQUID CRYSTALS PLATYPUS TECHNOLOGIES, LLC 2017-07-27 US disclosed
US-9575037-B2 Detection of gas-phase analytes using liquid crystals PLATYPUS TECHNOLOGIES, LLC (US) 2017-02-21 US disclosed
US-4511729-A Nucleophilic substitution process ETHYL CORPORATION (US) 1985-04-16 US disclosed
US-4511729-A Nucleophilic substitution process ETHYL CORPORATION (US) 1985-04-16 US disclosed
US-4502998-A Nucleophilic substitution process ETHYL CORPORATION (US) 1985-03-05 US disclosed
US-4502998-A Nucleophilic substitution process ETHYL CORPORATION (US) 1985-03-05 US disclosed
EP-0102476-A1 Method of modulating the immune response system in mammals AMERICAN CYANAMID COMPANY (US) 1984-03-14 EP disclosed
US-4277398-A ORANGE-COLORED, COUNTERACTING UNWANTED ABSORPTION OF MAGENTA DYES IN COLOR PHOTOGRAPHY CIBA-GEIGY AG (CH) 1981-07-07 US disclosed
US-3988467-A Aminoacyl compounds CIBA-GEIGY CORPORATION (US) 1976-10-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210403456-A1 HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF EPILEPSY SLC6A11, SCN1A, SCN1B MEN1 450/4885KMT2A 279/4885MAPT 741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.