SCHEMBL4163584

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4164482	0.86	MAPT (0.56)	MAPTALDH1A1KDM4EGAAL3MBTL1
	SCHEMBL4163391	0.84	ALDH1A1 (0.55)	MAPTALDH1A1KDM4EGAAL3MBTL1
	SCHEMBL4165178	0.78	MIF (0.49)	MAPTALDH1A1SMN1; SMN2RAB9ANPC1
	SCHEMBL4158016	0.74	MAPT (0.53)	MAPTALDH1A1KDM4EL3MBTL1SMN1; SMN2
	SCHEMBL4163664	0.74	MAPT (0.68)	MAPTALDH1A1GAAL3MBTL1SMN1; SMN2
	SCHEMBL4159205	0.74	DRD1 (0.43)	MAPTALDH1A1KDM4EGAAL3MBTL1
	SCHEMBL4159194	0.73	MAPT (0.45)	MAPTALDH1A1KDM4EGAAL3MBTL1
	SCHEMBL4160623	0.73	MAPT (0.54)	MAPTALDH1A1KDM4EL3MBTL1SMN1; SMN2
	SCHEMBL4174201	0.73	MAPT (0.46)	MAPTALDH1A1KDM4EL3MBTL1SMN1; SMN2
	SCHEMBL4157916	0.73	MAPT (0.45)	MAPTALDH1A1KDM4EGAAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.