SCHEMBL4159205

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4164482	0.80	MAPT (0.56)	ALDH1A1MEN1KMT2APOLBMAPT
	SCHEMBL4171149	0.76	MIF (0.38)	DRD1ALDH1A1MEN1KMT2ANR3C2
	SCHEMBL4159725	0.76	ALDH1A1 (0.46)	DRD1ALDH1A1MEN1KMT2APOLB
	SCHEMBL4163584	0.74	MAPT (0.44)	ALDH1A1MEN1KMT2APOLBNR3C2
	SCHEMBL4162365	0.72	MAPT (0.48)	DRD1ALDH1A1MEN1KMT2ANR3C2
	SCHEMBL4163391	0.72	ALDH1A1 (0.55)	ALDH1A1MAPTL3MBTL1GAAKDM4E
	SCHEMBL15678969	0.71	POLB (0.45)	DRD1ALDH1A1MEN1KMT2APOLB
	SCHEMBL4165324	0.70	CES1 (0.41)	DRD1ALDH1A1MEN1KMT2APOLB
	SCHEMBL4160618	0.70	MAPT (0.56)	DRD1ALDH1A1MEN1KMT2ANR3C2
	SCHEMBL4161069	0.70	LMNA (0.48)	DRD1ALDH1A1MEN1KMT2ANR3C2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.