SCHEMBL4163701

SCHEMBL4163701

CC(=O)NCC1CN(c2ccc(-c3ccc(N4CCNCC4)c(F)c3)c(F)c2)C(=O)O1

nearest known ligand 0.70

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.70
MAOB P27338 5/20 0.70
PTGS1 P23219 2/20 0.70
SDHA P31040 2/20 0.70
CALML3 P27482 2/20 0.70
LMNA P02545 1/20 0.70
F10 P00742 6/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1894257 0.93 MAOA (0.80) MAOAMAOBPTGS1SDHACALML3
SCHEMBL1498511 0.93 MAOA (0.80) MAOAMAOBPTGS1SDHACALML3
SCHEMBL4168125 0.92 MAOA (0.74) MAOAMAOBPTGS1SDHACALML3
SCHEMBL4168120 0.92 MAOA (0.74) MAOAMAOBPTGS1SDHACALML3
Hydrochloric Acid SCHEMBL4689047 0.92 MAOA (0.79) MAOAMAOBPTGS1SDHACALML3
Hydrochloric Acid SCHEMBL4689051 0.92 MAOA (0.79) MAOAMAOBPTGS1SDHACALML3
SCHEMBL5818098 0.91 MAOA (0.75) MAOAMAOBPTGS1SDHACALML3
SCHEMBL4181827 0.91 MAOA (0.71) MAOAMAOBPTGS1SDHACALML3
SCHEMBL4181831 0.91 MAOA (0.71) MAOAMAOBPTGS1SDHACALML3
SCHEMBL4179257 0.90 MAOA (0.70) MAOAMAOBPTGS1SDHACALML3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090018123-A1 Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation SINDKHEDKAR MILIND D 2009-01-15 US disclosed
EP-1912980-A2 OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION Wockhardt Limited (IN) 2008-04-23 EP disclosed
WO-2007023507-A2 OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION WOCKHARDT LIMITED (IN) 2007-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090018123-A1 Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation POLL, POLM, POLRMT MAOA 3788/4885MAOB 3240/4885PTGS1 3683/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.