SCHEMBL1498511

SCHEMBL1498511

CC(=O)NCC1CN(c2ccc(N3CCNCC3)c(F)c2)C(=O)O1

nearest known ligand 0.80

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.80
MAOB P27338 6/20 0.80
PTGS1 P23219 2/20 0.80
SDHA P31040 2/20 0.80
LMNA P02545 1/20 0.80
CALML3 P27482 1/20 0.80
F10 P00742 7/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1894257 1.00 MAOA (0.80) MAOAMAOBPTGS1SDHALMNA
Hydrochloric Acid SCHEMBL4689047 0.99 MAOA (0.79) MAOAMAOBPTGS1SDHALMNA
Hydrochloric Acid SCHEMBL4689051 0.99 MAOA (0.79) MAOAMAOBPTGS1SDHALMNA
SCHEMBL5818098 0.96 MAOA (0.75) MAOAMAOBPTGS1SDHALMNA
Phosphonic Acid SCHEMBL5325175 0.96 MAOB (0.75) MAOAMAOBPTGS1SDHALMNA
Trifluoroacetic Acid SCHEMBL5943313 0.95 MAOB (0.73) MAOAMAOBPTGS1SDHALMNA
Trifluoroacetic Acid SCHEMBL6509850 0.95 MAOB (0.73) MAOAMAOBPTGS1SDHALMNA
Trifluoroacetic Acid SCHEMBL5727900 0.95 MAOB (0.73) MAOAMAOBPTGS1SDHALMNA
SCHEMBL10151522 0.94 MAOA (0.80) MAOAMAOBPTGS1SDHALMNA
SCHEMBL4163701 0.93 MAOA (0.70) MAOAMAOBPTGS1SDHALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117222433-A Medicaments conjugated to hexose phosphate and methods of making and using the same 密西西比州立大学 2023-12-12 CN claimed
US-20230372492-A1 DRUGS CONJUGATED WITH HEXOSE PHOSPHATE AND METHODS OF MAKING AND USING SAME MISSISSIPPI STATE UNIVERSITY (US) 2023-11-23 US claimed
WO-2007138381-A2 PHOSPHONATED OXAZOLIDINONES AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS TARGANTA THERAPEUTICS INC. (CA) 2007-12-06 WO claimed
CN-1237056-C Oxazolidone compound, preparing method and use thereof SHANGHAI DRUG INST CHINESE ACA (CN) 2006-01-18 CN claimed
EP-4219437-B1 BAKUCHIOL DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF JIANGXI SHIMEI PHARMACEUTICAL CO LTD (CN) 2025-04-16 EP disclosed
US-11912650-B2 Bakuchiol derivatives, pharmaceutically acceptable salts thereof, and preparation method and use of the same JIANGXI SHIMEI PHARMACEUTICAL CO., LTD (CN) 2024-02-27 US disclosed
CN-117222433-A Medicaments conjugated to hexose phosphate and methods of making and using the same 密西西比州立大学 2023-12-12 CN disclosed
US-20230372492-A1 DRUGS CONJUGATED WITH HEXOSE PHOSPHATE AND METHODS OF MAKING AND USING SAME MISSISSIPPI STATE UNIVERSITY (US) 2023-11-23 US disclosed
EP-4219437-A1 BAKUCHIOL DERIVATIVE, PHARMACEUTICALLY ACCEPTABLE SALT THEREOF, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF Jiangxi Shimei Pharmaceutical Co., Ltd. (CN) 2023-08-02 EP disclosed
CN-113896620-B Bavacrol derivatives, pharmaceutically acceptable salts thereof, and preparation method and application thereof 江西施美药业股份有限公司 2022-11-15 CN disclosed
CN-113896620-A Bavacrol derivatives, pharmaceutically acceptable salts thereof, and preparation method and application thereof 江西施美药业股份有限公司 2022-01-07 CN disclosed
EP-2254892-B1 BICYCLIC NITROIMIDAZOLES COVALENTLY LINKED TO SUBSTITUTED PHENYL OXAZOLIDINONES GLOBAL ALLIANCE FOR TB DRUG DEV (US) 2014-04-23 EP disclosed
WO-2002006278-A1 OXAZOLIDINONE DERIVATIVES AS ANTIMICROBIALS RANBAXY LABORATORIES LIMITED (IN) 2002-01-24 WO disclosed
EP-0730591-B1 ESTERS OF SUBSTITUTED-HYDROXYACETYL PIPERAZINE PHENYL OXAZOLIDINONES UPJOHN CO (US) 1999-07-14 EP disclosed
US-5652238-A WATER SOLUBILITY; ANTIMICROBIAL AGENTS EFFECTIVE AGAINST RESISTANT STAPHYLOCOCCI, ENTEROCOCCI, AND STREPTOCOCCI PHARMACIA & UPJOHN COMPANY (US) 1997-07-29 US disclosed
EP-0730591-A1 ESTERS OF SUBSTITUTED-HYDROXYACETYL PIPERAZINE PHENYL OXAZOLIDINONES PHARMACIA & UPJOHN COMPANY (US) 1996-09-11 EP disclosed
US-5547950-A FOR TREATING DRUG RESISTANT STAPHYLOCOCCUS AND STREPTOCOCCUS INFECTIONS THE UPJOHN COMPANY (US) 1996-08-20 US disclosed
WO-1995014684-A1 ESTERS OF SUBSTITUTED-HYDROXYACETYL PIPERAZINE PHENYL OXAZOLIDINONES THE UPJOHN COMPANY (US) 1995-06-01 WO disclosed
EP-0640077-A1 OXAZOLIDINONES CONTAINING A SUBSTITUTED DIAZINE MOIETY AND THEIR USE AS ANTIMICROBIALS PHARMACIA & UPJOHN COMPANY (US) 1995-03-01 EP disclosed
WO-1993023384-A1 OXAZOLIDINONES CONTAINING A SUBSTITUTED DIAZINE MOIETY AND THEIR USE AS ANTIMICROBIALS THE UPJOHN COMPANY (US) 1993-11-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230372492-A1 DRUGS CONJUGATED WITH HEXOSE PHOSPHATE AND METHODS OF MAKING AND USING SAME GFPT1, PHPT1, SLC2A1 MAOA 2364/4885MAOB 3136/4885PTGS1 3999/4885
US-11912650-B2 Bakuchiol derivatives, pharmaceutically acceptable salts thereof, and preparation method and use of the same CEL, NPC1L1, LIPA MAOA 1939/4885MAOB 2396/4885PTGS1 1883/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.