Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 7/20 | 0.58 |
| ▸ | HSP90AB1 | P08238 | 7/20 | 0.58 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.44 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.44 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13740945 | 1.00 | HSP90AA1 (0.58) | HSP90AA1HSP90AB1ROCK2PDK1PDK2 | |
| SCHEMBL19475037 | 0.81 | HSP90AA1 (0.66) | HSP90AA1HSP90AB1PDK1PDK2PDK3 | |
| SCHEMBL4150811 | 0.78 | HSP90AA1 (0.60) | HSP90AA1HSP90AB1PDK1PDK2PDK3 | |
| SCHEMBL4157014 | 0.78 | HSP90AA1 (0.60) | HSP90AA1HSP90AB1PDK1PDK2PDK3 | |
| SCHEMBL14905799 | 0.77 | CXCR1 (0.49) | ROCK2CXCR1CXCR2KLK7 | |
| SCHEMBL5416477 | 0.76 | ROCK2 (0.46) | ROCK2PDK2CXCR1CXCR2KLK7 | |
| SCHEMBL15473578 | 0.75 | HCRTR1 (0.48) | ROCK2CXCR1CXCR2KLK7 | |
| SCHEMBL8637778 | 0.75 | ROCK2 (0.47) | ROCK2CXCR1CXCR2KLK7 | |
| SCHEMBL5568044 | 0.75 | MEN1 (0.45) | ROCK2CXCR1CXCR2KLK7 | |
| SCHEMBL14905797 | 0.74 | CXCR1 (0.47) | ROCK2CXCR1CXCR2KLK7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | claimed |
| EP-1879863-A1 | AMIDE RESORCINOL COMPOUNDS | Pfizer, Inc. (US) | 2008-01-23 | — | — | EP | claimed |
| WO-2006117669-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER INC. (US) | 2006-11-09 | — | — | WO | claimed |
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER, INC. | 2009-08-27 | — | — | US | disclosed |
| EP-1879863-A1 | AMIDE RESORCINOL COMPOUNDS | Pfizer, Inc. (US) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006117669-A1 | AMIDE RESORCINOL COMPOUNDS | PFIZER INC. (US) | 2006-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090215742-A1 | AMIDE RESORCINOL COMPOUNDS | HSP90AB1, HSP90AA1, HSP90AB2P | HSP90AA1 2/4885HSP90AB1 1/4885ROCK2 1403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.