Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ILK | Q13418 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL353413 | 0.83 | CYP1A2 (0.44) | ALDH1A1CYP1A2LMNACYP3A4MAOA | |
| SCHEMBL5767934 | 0.81 | TSHR (0.52) | ALDH1A1HSD17B10CYP1A2MEN1KMT2A | |
| SCHEMBL29922777 | 0.77 | BRD4 (0.60) | ALDH1A1HSD17B10CYP1A2LMNACYP3A4 | |
| SCHEMBL1187172 | 0.77 | BRD4 (0.60) | ALDH1A1HSD17B10CYP1A2LMNACYP3A4 | |
| SCHEMBL4169677 | 0.77 | ALDH1A1 (0.51) | ALDH1A1HSD17B10CYP1A2LMNACYP3A4 | |
| SCHEMBL26081243 | 0.75 | TSHR (0.49) | ALDH1A1HSD17B10CYP1A2MEN1KMT2A | |
| SCHEMBL22140520 | 0.75 | ALDH1A1 (0.49) | ALDH1A1HSD17B10CYP1A2LMNACYP3A4 | |
| SCHEMBL6896843 | 0.75 | ALDH1A1 (0.49) | ALDH1A1HSD17B10CYP1A2LMNACYP3A4 | |
| SCHEMBL31282770 | 0.75 | ALDH1A1 (0.49) | ALDH1A1HSD17B10CYP1A2LMNACYP3A4 | |
| SCHEMBL25242507 | 0.74 | TP53 (0.41) | HSD17B10CYP1A2KDM4ETP53ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069333-A1 | FUNGICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2009-03-12 | — | — | US | disclosed |
| US-7410967-B2 | Pyridodiazines as plant fungicides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-08-12 | — | — | US | disclosed |
| EP-1575948-B1 | PYRIDODIAZINES AS PLANT FUNGICIDES | SYNGENTA LTD (GB) | 2007-02-14 | — | — | EP | disclosed |
| US-20060205717-A1 | Pyridodiazines as plant fungicides | SYNGENTA CROP PROTECTION, INC. | 2006-09-14 | — | — | US | disclosed |
| EP-1575948-A1 | PYRIDODIAZINES AS PLANT FUNGICIDES | Syngenta Limited (GB) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004056825-A1 | PYRIDODIAZINES AS PLANT FUNGICIDES | SYNGENTA LIMITED (GB) | 2004-07-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069333-A1 | FUNGICIDES | CYP4Z1, CYP4X1, PRXL2A | ALDH1A1 1469/4885HSD17B10 2955/4885CYP1A2 4/4885 |
| US-20060205717-A1 | Pyridodiazines as plant fungicides | CYP4Z1, CYP4X1, PNPO | ALDH1A1 917/4885HSD17B10 2029/4885CYP1A2 14/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.