Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methimazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methimazole SCHEMBL11566410 | 0.97 | — | — | |
| Methimazole SCHEMBL2267872 | 0.97 | — | — | |
| Methimazole SCHEMBL17287217 | 0.97 | — | — | |
| Methimazole SCHEMBL28774524 | 0.97 | — | — | |
| Methimazole SCHEMBL6189739 | 0.97 | — | — | |
| Methimazole SCHEMBL11405758 | 0.89 | LPO (0.41) | — | |
| Methimazole SCHEMBL28849331 | 0.89 | LPO (0.41) | — | |
| Methimazole SCHEMBL25206387 | 0.85 | LPO (0.39) | — | |
| Methimazole SCHEMBL10436346 | 0.83 | LPO (0.38) | — | |
| Methimazole SCHEMBL10935910 | 0.82 | KMT2A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 11941 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122076543-A | Preparation method and application of graded round table porous synergistic light trapping SERS substrate | — | 2026-05-26 | — | — | CN | claimed |
| CN-117101424-B | Method for preparing defect-free MOF film by MOF gradient distribution seeding mode | 大连理工大学 | 2026-05-22 | — | — | CN | claimed |
| CN-119798128-B | Preparation method of dicumyl peroxide | 万华化学集团股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| CN-122054800-A | Perovskite battery, preparation method thereof and photovoltaic module | 东方日升新能源股份有限公司 | 2026-05-15 | — | — | CN | claimed |
| CN-122010656-A | Application of oxyalkylisourea in introducing methyl and isotopically-labeled methyl | 陕西师范大学 | 2026-05-12 | — | — | CN | claimed |
| EP-4724042-A1 | METHOD FOR IMPROVING THE INGESTION OF A LIQUID OR VISCOUS SUBSTANCE | Ceva Santé Animale (FR) | 2026-04-15 | — | — | EP | claimed |
| US-20260069522-A1 | SKIN DEPIGMENTATION COMPOSITION AND USE THEREOF | KASRAEE BEHROOZ (CH) | 2026-03-12 | — | — | US | claimed |
| US-12575418-B2 | Semiconductor packages having organic material layer between through-via structure and encapsulant that surrounds a portion of semiconductor chip | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2026-03-10 | — | — | US | claimed |
| CN-121575407-A | Alkaline super-roughening solution, preparation method thereof and super-roughening method | 深圳市板明科技股份有限公司 | 2026-02-27 | — | — | CN | claimed |
| US-12550694-B2 | Selective deposition for integrated circuit interconnect structures | TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. (TW) | 2026-02-10 | — | — | US | claimed |
| EP-0058044-B1 | ELECTRODEPOSITION OF CHROMIUM | W. CANNING MATERIALS LIMITED (GB) | 1986-06-18 | — | — | EP | claimed |
| US-4546155-A | ADDUCT OF EPOXY COMPOUND, TERTIARY AMINE COMPOUND, AND CARBOXYLIC ACID ANHYDRIDE | AJINOMOTO CO., INC. (JP) | 1985-10-08 | — | — | US | claimed |
| EP-0141777-A2 | Herbicidal sulfonyl urea | CIBA-GEIGY AG (CH) | 1985-05-15 | — | — | EP | claimed |
| US-4473448-A | Electrodeposition of chromium | W. CANNING MATERIALS LIMITED (GB) | 1984-09-25 | — | — | US | claimed |
| EP-0058044-A1 | Electrodeposition of chromium | W. CANNING MATERIALS LIMITED (GB) | 1982-08-18 | — | — | EP | claimed |
| EP-0038541-A1 | Novel prodrugs of biologically active agents containing mercapto groups, process for preparing and therapeutically effective composition containing the same | MERCK & CO. INC. (US) | 1981-10-28 | — | — | EP | claimed |
| US-4283477-A | POLYSULFONAMIDE SEPARATION POLYMER FOR STORAGE STABILITY | EASTMAN KODAK COMPANY (US) | 1981-08-11 | — | — | US | claimed |
| US-4217239-A | Composition for scintillation counting | CIBA-GEIGY CORPORATION (US) | 1980-08-12 | — | — | US | claimed |
| US-4168980-A | SILVER IMIDAZOLINE-2-THIONE | EASTMAN KODAK COMPANY (US) | 1979-09-25 | — | — | US | claimed |
| US-3954732-A | BACTERICIDAL PENICILLINS | FUJISAWA PHARMACEUTICAL CO., LTD. (JA) | 1976-05-04 | — | — | US | claimed |