Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | SI | P14410 | 1/20 | 0.48 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3139713 | 0.83 | LMNA (0.57) | EPHX2TSHRPOLBMGAMGAA | |
| SCHEMBL6807458 | 0.79 | EPHX2 (0.50) | EPHX2TSHRPOLBMGAMGAA | |
| SCHEMBL6803163 | 0.79 | EPHX2 (0.74) | EPHX2TSHRPOLBALDH1A1LOXL2 | |
| SCHEMBL34467481 | 0.78 | EPHX2 (0.49) | EPHX2TSHRPOLBALDH1A1HPGD | |
| SCHEMBL4723305 | 0.76 | EPHX2 (0.66) | EPHX2TSHRPOLBGAAALDH1A1 | |
| SCHEMBL963712 | 0.76 | EPHX2 (0.70) | EPHX2TSHRPOLBGAAALDH1A1 | |
| SCHEMBL3136047 | 0.76 | EPHX2 (0.70) | EPHX2TSHRPOLBGAAALDH1A1 | |
| SCHEMBL14341905 | 0.76 | EPHX2 (1.00) | EPHX2TSHRPOLBALDH1A1MAPT | |
| SCHEMBL231214 | 0.76 | EPHX2 (0.70) | EPHX2TSHRPOLBMGAMGAA | |
| SCHEMBL27674641 | 0.76 | EPHX2 (0.70) | EPHX2TSHRPOLBMGAMGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2007071840-A2 | COMPOUNDS BASED ON FOUR AROMATIC RINGS, PREPARATION AND USES THEREOF | CEREP (FR) | 2007-06-28 | — | — | WO | disclosed |
| US-6794378-B2 | ANTIINFLAMMATORY AGENTS | AJINOMOTO CO., INC. (JP) | 2004-09-21 | — | — | US | disclosed |
| US-20020133005-A1 | Heterocyclic compounds and medical use thereof | AJINOMOTO CO., INC. (JP) | 2002-09-19 | — | — | US | disclosed |
| EP-1193255-A1 | HETEROCYCLIC COMPOUNDS AND MEDICINAL USE THEREOF | Ajinomoto Co., Inc. (JP) | 2002-04-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020133005-A1 | Heterocyclic compounds and medical use thereof | NFKBIA, CHUK, RELA | EPHX2 2556/4885TSHR 4622/4885POLB 4103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.