Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MGAM | O43451 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | SI | P14410 | 2/20 | 0.47 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 4/20 | 0.42 |
| ▸ | GSK3B | P49841 | 4/20 | 0.42 |
| ▸ | AURKA | O14965 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3144944 | 0.79 | ALDH1A1 (0.49) | EPHX2TSHRPOLBMGAMGAA | |
| SCHEMBL4164786 | 0.79 | EPHX2 (0.60) | EPHX2TSHRPOLBMGAMGAA | |
| SCHEMBL32679855 | 0.75 | ALDH1A1 (0.70) | TSHRALDH1A1TDP1GSK3AGSK3B | |
| SCHEMBL34467481 | 0.75 | EPHX2 (0.49) | EPHX2TSHRPOLBALDH1A1TDP1 | |
| SCHEMBL219638 | 0.74 | MGAM (0.57) | MGAMGAASIMGAM2ALDH1A1 | |
| SCHEMBL231242 | 0.73 | EPHX2 (0.69) | EPHX2TSHRPOLBALDH1A1TDP1 | |
| SCHEMBL8701556 | 0.72 | ALDH1A1 (0.65) | TSHRMGAMGAASIMGAM2 | |
| SCHEMBL3139713 | 0.72 | LMNA (0.57) | EPHX2TSHRPOLBMGAMGAA | |
| SCHEMBL7785924 | 0.71 | ALDH1A1 (0.67) | TSHRGAAALDH1A1TDP1HPGD | |
| SCHEMBL6803163 | 0.70 | EPHX2 (0.74) | EPHX2TSHRPOLBALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6794378-B2 | ANTIINFLAMMATORY AGENTS | AJINOMOTO CO., INC. (JP) | 2004-09-21 | — | — | US | disclosed |