Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 known ✓ | P08588 | 1/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 7/20 | 0.58 |
| ▸ | DNMT3B | Q9UBC3 | 3/20 | 0.53 |
| ▸ | PNP | P00491 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 2/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.45 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12731448 | 0.95 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BPNPLMNA | |
| SCHEMBL5982343 | 0.95 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BPNPLMNA | |
| SCHEMBL197813 | 0.95 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BPNPLMNA | |
| SCHEMBL5982335 | 0.95 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BPNPLMNA | |
| SCHEMBL198512 | 0.95 | DNMT1 (0.63) | DNMT1ADRB1DNMT3BPNPLMNA | |
| Phosphoric Acid SCHEMBL6460717 | 0.88 | DNMT1 (0.60) | DNMT1ADRB1DNMT3BPNPLMNA | |
| SCHEMBL9780823 | 0.87 | DNMT1 (0.52) | DNMT1ADRB1DNMT3BPNPLMNA | |
| SCHEMBL9780830 | 0.87 | DNMT1 (0.52) | DNMT1ADRB1DNMT3BPNPLMNA | |
| SCHEMBL3470530 | 0.87 | POLB (0.55) | — | |
| Phosphoric Acid SCHEMBL8603092 | 0.87 | DNMT1 (0.58) | DNMT1ADRB1DNMT3BPNPLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120021427-A1 | Methods For Rapid Forensic DNA Analysis | IBIS BIOSCIENCE, INC (US) | 2012-01-26 | — | — | US | disclosed |