Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 5/20 | 0.55 |
| ▸ | ACE | P12821 | 1/20 | 0.50 |
| ▸ | CALCR | P30988 | 3/20 | 0.47 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.45 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416628 | 1.00 | OPRK1 (0.55) | OPRK1ACECALCRNMUR2NMUR1 | |
| SCHEMBL417342 | 0.90 | OPRK1 (0.44) | OPRK1ACECALCR | |
| SCHEMBL417341 | 0.90 | OPRK1 (0.44) | OPRK1ACECALCR | |
| SCHEMBL416569 | 0.88 | OPRK1 (0.45) | OPRK1ACE | |
| SCHEMBL416570 | 0.88 | OPRK1 (0.45) | OPRK1ACE | |
| SCHEMBL416535 | 0.88 | OPRK1 (0.46) | OPRK1ACE | |
| SCHEMBL416536 | 0.88 | OPRK1 (0.46) | OPRK1ACE | |
| SCHEMBL30799121 | 0.87 | ACE (0.57) | OPRK1ACEOPRM1 | |
| SCHEMBL30798900 | 0.84 | ACE (0.55) | OPRK1ACEOPRM1 | |
| SCHEMBL417518 | 0.84 | OPRM1 (0.45) | CALCROPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103585105-A | Sphingolipid activator protein C for transmembrane medicine delivering system as well as associated protein and peptide-promoted fusion protein | CHILDRENS HOSP MEDICAL CENTER | 2014-02-19 | — | — | CN | claimed |
| US-20120020878-A1 | FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2012-01-26 | — | — | US | claimed |
| CN-102264349-A | Sphingolipid activator protein C and related protein and peptide fusogenic properties for transmembrane drug delivery systems | — | 2011-11-30 | — | — | CN | claimed |
| EP-2365796-A1 | FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS | Children's Hospital Medical Center (US) | 2011-09-21 | — | — | EP | claimed |
| WO-2010053489-A1 | FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2010-05-14 | — | — | WO | claimed |
| CN-103585105-A | Sphingolipid activator protein C for transmembrane medicine delivering system as well as associated protein and peptide-promoted fusion protein | CHILDRENS HOSP MEDICAL CENTER | 2014-02-19 | — | — | CN | disclosed |
| US-20120020878-A1 | FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2012-01-26 | — | — | US | disclosed |
| CN-102264349-A | Sphingolipid activator protein C and related protein and peptide fusogenic properties for transmembrane drug delivery systems | — | 2011-11-30 | — | — | CN | disclosed |
| EP-2365796-A1 | FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS | Children's Hospital Medical Center (US) | 2011-09-21 | — | — | EP | disclosed |
| WO-2010053489-A1 | FUSOGENIC PROPERTIES OF SAPOSIN C AND RELATED PROTEINS AND PEPTIDES FOR APPLICATION TO TRANSMEMBRANE DRUG DELIVERY SYSTEMS | CHILDREN'S HOSPITAL MEDICAL CENTER (US) | 2010-05-14 | — | — | WO | disclosed |