Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.51 |
| ▸ | ACE | P12821 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4167694 | 0.89 | POLB (0.63) | L3MBTL1KMT2AITGB1ITGA4PTPN1 | |
| SCHEMBL4177396 | 0.88 | ATM (0.58) | L3MBTL1NPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL30118392 | 0.86 | L3MBTL1 (0.74) | L3MBTL1KMT2ASMN1; SMN2ITGB1ITGA4 | |
| SCHEMBL9716620 | 0.86 | L3MBTL1 (0.74) | L3MBTL1KMT2ASMN1; SMN2ITGB1ITGA4 | |
| SCHEMBL16993893 | 0.86 | L3MBTL1 (0.74) | L3MBTL1KMT2ASMN1; SMN2ITGB1ITGA4 | |
| SCHEMBL4170016 | 0.83 | L3MBTL1 (0.79) | L3MBTL1KMT2AITGB1ITGA4PTPN1 | |
| SCHEMBL10526607 | 0.83 | PTPN1 (0.70) | L3MBTL1KMT2ARAB9APTPN1CA2 | |
| SCHEMBL4682004 | 0.83 | PTPN1 (0.70) | L3MBTL1KMT2ARAB9APTPN1CA2 | |
| SCHEMBL4166657 | 0.83 | PTPN1 (0.70) | L3MBTL1KMT2ARAB9APTPN1CA2 | |
| SCHEMBL28360264 | 0.81 | L3MBTL1 (0.67) | L3MBTL1KMT2AITGB1ITGA4PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | DEWIS MARK L | 2009-02-19 | — | — | US | disclosed |
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | DEWIS MARK L | 2009-02-19 | — | — | US | disclosed |
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | DEWIS MARK L | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090047379-A1 | Benzamide Compounds Useful as High Potency Sweet Taste Enhancers | TAS2R10, TAS2R50, TAS2R8 | L3MBTL1 4231/4885KMT2A 378/4885NPC1 2029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.