Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MLYCD | O95822 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1003735 | 0.93 | TP53 (0.68) | TP53HDAC1HDAC6HPGDALDH1A1 | |
| SCHEMBL5166929 | 0.85 | HPGD (0.68) | TP53HDAC1HDAC6HPGDALDH1A1 | |
| SCHEMBL9694832 | 0.82 | MLYCD (0.72) | TP53HDAC1HDAC6HPGDALDH1A1 | |
| SCHEMBL1926269 | 0.82 | HDAC1 (0.73) | TP53HDAC1HDAC6ALDH1A1LIMK1 | |
| SCHEMBL28149291 | 0.82 | ALDH1A1 (0.74) | TP53HDAC1HDAC6HPGDALDH1A1 | |
| SCHEMBL1004032 | 0.81 | HPGD (0.71) | TP53HDAC1HDAC6HPGDALDH1A1 | |
| SCHEMBL9361376 | 0.79 | TP53 (0.60) | TP53HDAC1HDAC6HPGDALDH1A1 | |
| SCHEMBL26314066 | 0.79 | MLYCD (0.64) | TP53HDAC1HDAC6HPGDALDH1A1 | |
| SCHEMBL28497560 | 0.79 | HDAC1 (0.54) | TP53HDAC1HDAC6HPGDALDH1A1 | |
| SCHEMBL19404639 | 0.79 | TP53 (0.51) | TP53HDAC1HDAC6HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | LABORATORIOS SALVAT, S.A. (ES) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090088438-A1 | NEW TYROSINE DERIVATIVES AS PPARy MODULATORS | PPARG, PPARD, TYRO3 | TP53 1939/4885HDAC1 1912/4885HDAC6 1947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.