SCHEMBL1003735

SCHEMBL1003735

CCCN(CCC)C(=O)c1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.68
HDAC1 Q13547 2/20 0.62
HDAC6 Q9UBN7 2/20 0.62
HPGD P15428 4/20 0.61
ALDH1A1 P00352 2/20 0.61
MLYCD O95822 1/20 0.61
EGFR P00533 1/20 0.57
ERBB2 P04626 1/20 0.57
MAPT P10636 1/20 0.56
GAA P10253 1/20 0.56
LIMK1 P53667 1/20 0.51
HTR1A P08908 1/20 0.51
DRD2 P14416 1/20 0.51
HTR2A P28223 1/20 0.51
OPRM1 P35372 1/20 0.50
OPRD1 P41143 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4167802 0.93 TP53 (0.59) TP53HDAC1HDAC6HPGDALDH1A1
SCHEMBL5166929 0.92 HPGD (0.68) TP53HDAC1HDAC6HPGDALDH1A1
SCHEMBL9694832 0.89 MLYCD (0.72) TP53HDAC1HDAC6HPGDALDH1A1
SCHEMBL28149291 0.89 ALDH1A1 (0.74) TP53HDAC1HDAC6HPGDALDH1A1
SCHEMBL1926269 0.89 HDAC1 (0.73) TP53HDAC1HDAC6ALDH1A1LIMK1
SCHEMBL1004032 0.88 HPGD (0.71) TP53HDAC1HDAC6HPGDALDH1A1
SCHEMBL9361376 0.86 TP53 (0.60) TP53HDAC1HDAC6HPGDALDH1A1
SCHEMBL26314066 0.86 MLYCD (0.64) TP53HDAC1HDAC6HPGDALDH1A1
SCHEMBL28497560 0.86 HDAC1 (0.54) TP53HDAC1HDAC6HPGDALDH1A1
SCHEMBL19404639 0.85 TP53 (0.51) TP53HDAC1HDAC6HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727996-A1 METHOD FOR REMOVAL OF ADDITIVES FROM A POLYMERIC MATERIAL BASF SE (DE) 2026-04-22 EP claimed
WO-2024260970-A1 METHOD FOR REMOVAL OF ADDITIVES FROM A POLYMERIC MATERIAL BASF SE (DE) 2024-12-26 WO claimed
CN-101084235-A 3-deoxyglucosone and skin DYNAMIS THERAPEUTICS INC (US) 2007-12-05 CN claimed
US-20070225291-A1 Substituted Pyrazinone Compounds for the Treatment of Inflammation PFIZER INC. 2007-09-27 US claimed
EP-1678164-B1 SUBSTITUTED PYRAZINONE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION PHARMACIA CORP (US) 2007-04-11 EP claimed
CN-1882544-A Benzylether and benzylamino beta-secretase inhibitors for the treatment of alzheimer s disease MERCK & CO INC (US) 2006-12-20 CN claimed
EP-1678146-A1 PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION Pharmacia Corporation (US) 2006-07-12 EP claimed
EP-1678164-A1 SUBSTITUTED PYRAZINONE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION Pharmacia Corporation (US) 2006-07-12 EP claimed
CN-1759095-A N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives ELAN PHARM INC (US) 2006-04-12 CN claimed
US-20050197338-A1 Substituted pyrazole urea compounds for the treatment of inflammation PHARMACIA AND UPJOHN COMPANY LLC 2005-09-08 US claimed
WO-2003047572-A1 USE OF 1-PHENYL-OXAZOLIDINE-2-ONE COMPOUNDS AS PROTEASE M INHIBITORS MERCK PATENT GMBH (DE) 2003-06-12 WO claimed
US-20030103915-A1 Combinations of sunscreens 3V SIGMA S.P.A. (IT) 2003-06-05 US claimed
EP-1300137-A2 Combinations of sunscreens 3V SIGMA S.p.A (IT) 2003-04-09 EP claimed
US-6514485-B1 Combinations of sunscreens 3V SIGMA S.P.A. (IT) 2003-02-04 US claimed
EP-0717982-B2 Process for photostabilizing of dibenzoylmethan derivatives of sunscreen agent, the photostable cosmetic sunscreen compositions and their use OREAL (FR) 2001-02-28 EP claimed
EP-1027883-A2 Combinations of sunscreen agents with UV-A and UV-B filtering properties 3V SIGMA S.p.A (IT) 2000-08-16 EP claimed
EP-0815834-A1 Photostable cosmetic sunscreen compositions containing a dibenzoylmethan derivative and an amide compound and their use L'OREAL (FR) 1998-01-07 EP claimed
US-5672337-A TOPICAL APPLICATION TO SKIN, HAIR L'OREAL (FR) 1997-09-30 US claimed
EP-0717982-B1 Process for photostabilizing of dibenzoylmethan derivatives of sunscreen agent, the photostable cosmetic sunscreen compositions and their use OREAL (FR) 1997-07-23 EP claimed
EP-0717982-A1 Process for photostabilizing of dibenzoylmethan derivatives of sunscreen agent, the photostable cosmetic sunscreen compositions and their use L'OREAL (FR) 1996-06-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050197338-A1 Substituted pyrazole urea compounds for the treatment of inflammation IL4, ARG2, CASP4 TP53 711/4885HDAC1 462/4885HDAC6 1341/4885
US-20070225291-A1 Substituted Pyrazinone Compounds for the Treatment of Inflammation CNKSR1, IL1RN, CHUK TP53 1071/4885HDAC1 280/4885HDAC6 925/4885
US-20030103915-A1 Combinations of sunscreens ERCC4, ERCC1, ERCC5 TP53 21/4885HDAC1 1200/4885HDAC6 682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.