SCHEMBL416790

SCHEMBL416790

C[Si](C)(OCC1CC2C=CC1C2)OCC1CC2C=CC1C2

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.42
ALDH1A1 P00352 3/20 0.42
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HTT P42858 1/20 0.35
TSHR P16473 1/20 0.34
POLB P06746 1/20 0.31
ALOX15 P16050 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24183336 1.00 KDM4E (0.42) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL417002 0.89 KDM4E (0.42) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL3037999 0.89 KDM4E (0.42) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL17563539 0.82 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL417051 0.82 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL417048 0.81 KDM4E (0.37) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL5335694 0.81 KDM4E (0.37) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL257223 0.78 KDM4E (0.46) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL4816311 0.78 KDM4E (0.46) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL19209884 0.78 KDM4E (0.41) KDM4EALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120077076-A Composition and method for producing the same 默克专利有限公司 2025-05-30 CN disclosed
EP-4437027-A1 DUAL UV BLOCKERS CONTAINING STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS Promerus, LLC (US) 2024-10-02 EP disclosed
US-20240287268-A1 RESIN FILM MURATA MANUFACTURING CO., LTD. (JP) 2024-08-29 US disclosed
CN-118317992-A Dual UV blocker comprising a shelf-life stable photoactive bulk polymerized polycycloolefin composition as an optical material 普罗米鲁斯有限责任公司 2024-07-09 CN disclosed
WO-2024083874-A1 COMPOSITION MERCK PATENT GMBH (DE) 2024-04-25 WO disclosed
WO-2024083874-A1 COMPOSITION MERCK PATENT GMBH (DE) 2024-04-25 WO disclosed
EP-4288479-A1 LONG SHELF LIFE STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS Promerus, LLC (US) 2023-12-13 EP disclosed
US-11795285-B2 Dual UV blockers containing stable photoactive mass polymerizable polycycloolefin compositions as optical materials PROMERUS, LLC (US) 2023-10-24 US disclosed
US-11795285-B2 Dual UV blockers containing stable photoactive mass polymerizable polycycloolefin compositions as optical materials PROMERUS, LLC (US) 2023-10-24 US disclosed
CN-116848170-A Photoactive bulk polymerized polycycloolefin compositions as optical materials that are shelf-life stable for extended periods of time 普罗米鲁斯有限责任公司 2023-10-03 CN disclosed
EP-1695128-A2 OPTICAL WAVEGUIDES AND METHODS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2006-08-30 EP disclosed
US-20050186502-A1 Directly photodefinable polymer compositions and methods thereof SUMITOMO BAKELITE CO., LTD. (JP) 2005-08-25 US disclosed
WO-2005076076-A2 DIRECTLY PHOTODEFINABLE POLYMER COMPOSITIONS AND METHODS THEREOF PROMERUS, LLC (US) 2005-08-18 WO disclosed
WO-2005052641-A2 OPTICAL WAVEGUIDES AND METHODS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2005-06-09 WO disclosed
US-6677175-B2 CURING A CLADDING LAYER TO FORM A CORE/CLADDING COMBINATION AND REMOVING THE CORE/CLADDING TO EXPOSE A PORTION OF THE CORE THAT HAS REFRACTIVE INDEX .05% HIGHER THAN THE CURED CLADDING COMPOSITION PROMERUS, LLC 2004-01-13 US disclosed
EP-1307493-A2 POLYMERIC COMPOSITIONS FOR FORMING OPTICAL WAVEGUIDES; OPTICAL WAVEGUIDES FORMED THEREFROM; AND METHODS FOR MAKING SAME Goodrich Corporation (US) 2003-05-07 EP disclosed
US-6538087-B2 (hetero)polycyclic polymer PROMERUS, LLC 2003-03-25 US disclosed
US-20020103317-A1 Polymeric compositions for forming optical waveguides; optical waveguides formed therefrom; and methods for making same SUMITOMO BAKELITE CO., LTD. (JP) 2002-08-01 US disclosed
US-20020064896-A1 Optical waveguides and methods for making the same 3M INNOVATIVE PROPERTIES COMPANY 2002-05-30 US disclosed
WO-2002010231-A2 POLYMERIC COMPOSITIONS FOR FORMING OPTICAL WAVEGUIDES; OPTICAL WAVEGUIDES FORMED THEREFROM; AND METHODS FOR MAKING SAME GOODRICH CORPORATION (US) 2002-02-07 WO disclosed