SCHEMBL417002

SCHEMBL417002

C[Si](OCC1CC2C=CC1C2)(OCC1CC2C=CC1C2)OCC1CC2C=CC1C2

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.42
ALDH1A1 P00352 3/20 0.42
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HTT P42858 1/20 0.35
TSHR P16473 1/20 0.34
POLB P06746 1/20 0.31
ALOX15 P16050 1/20 0.31
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3037999 0.89 KDM4E (0.42) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL24183336 0.89 KDM4E (0.42) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL416790 0.89 KDM4E (0.42) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL17563539 0.82 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL417051 0.82 KDM4E (0.38) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL417048 0.81 KDM4E (0.37) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL5335694 0.81 KDM4E (0.37) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL257223 0.78 KDM4E (0.46) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL4816311 0.78 KDM4E (0.46) KDM4EALDH1A1MEN1KMT2AHTT
SCHEMBL19209884 0.78 KDM4E (0.41) KDM4EALDH1A1MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4605438-A1 COMPOSITION Merck Patent GmbH (DE) 2025-08-27 EP disclosed
CN-118317992-A Dual UV blocker comprising a shelf-life stable photoactive bulk polymerized polycycloolefin composition as an optical material 普罗米鲁斯有限责任公司 2024-07-09 CN disclosed
WO-2024083874-A1 COMPOSITION MERCK PATENT GMBH (DE) 2024-04-25 WO disclosed
WO-2024083874-A1 COMPOSITION MERCK PATENT GMBH (DE) 2024-04-25 WO disclosed
EP-4288479-A1 LONG SHELF LIFE STABLE PHOTOACTIVE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS AS OPTICAL MATERIALS Promerus, LLC (US) 2023-12-13 EP disclosed
US-11795285-B2 Dual UV blockers containing stable photoactive mass polymerizable polycycloolefin compositions as optical materials PROMERUS, LLC (US) 2023-10-24 US disclosed
CN-116848170-A Photoactive bulk polymerized polycycloolefin compositions as optical materials that are shelf-life stable for extended periods of time 普罗米鲁斯有限责任公司 2023-10-03 CN disclosed
US-20230295452-A1 HIGH IMPACT STRENGTH 3D PRINTING MATERIALS DERIVED FROM POLYCYCLOOLEFIN MONOMERS AND CROSSLINKERS PROMERUS, LLC (US) 2023-09-21 US disclosed
US-11697744-B2 High impact strength 3D printing materials derived from polycycloolefin monomers and crosslinkers PROMERUS, LLC (US) 2023-07-11 US disclosed
US-11697744-B2 High impact strength 3D printing materials derived from polycycloolefin monomers and crosslinkers PROMERUS, LLC (US) 2023-07-11 US disclosed
US-20120241250-A1 Aerial Work Platforms and Aerial Work Platform Assemblies Comprised of Polymerized Cycloolefin Monomers EAKIN GEORGE R (US) 2012-09-27 US disclosed
US-8200058-B2 Light guide and light guide structure SUMITOMO BAKELITE COMPANY, LTD. (JP) 2012-06-12 US disclosed
US-20120064458-A1 OPTICAL WAVEGUIDES AND METHODS THEREOF PROMERUS, LLC (US) 2012-03-15 US disclosed
US-8053166-B2 Optical waveguides and methods thereof SUMITOMO BAKELITE CO. LTD. (JP) 2011-11-08 US disclosed
US-8021825-B2 Optical waveguides and methods thereof SUMITOMO BAKELITE CO., LTD. (JP) 2011-09-20 US disclosed
US-7820356-B2 photo-induced thermally developable film comprising norbornene-type polyalkenamer copolymer and a procatalyst; curable; transparent or colorless, and propagation loss SUMITOMO BAKELITE CO. LTD. (JP) 2010-10-26 US disclosed
US-20100067861-A1 LIGHT GUIDE AND LIGHT GUIDE STRUCTURE SUMITOMO BAKELITE COMPANY LIMITED (JP) 2010-03-18 US disclosed
US-20100061688-A1 OPTICAL WAVEGUIDES AND METHODS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2010-03-11 US disclosed
US-20100062378-A1 OPTICAL WAVEGUIDES AND METHODS THEREOF SUMITOMO BAKELITE CO., LTD. (JP) 2010-03-11 US disclosed
US-20070148566-A1 Optical waveguides and methods thereof SUMITOMO BAKELITE CO., LTD. (JP) 2007-06-28 US disclosed