SCHEMBL4403500

SCHEMBL4403500

CO[Si](CC[Si](C)(C)O[Si](C)(C)CCC1CC2C=CC1C2)(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 2/20 0.34
POLB P06746 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16418948 0.91 ALDH1A1 (0.36) ALDH1A1MEN1KMT2AKDM4E
SCHEMBL416791 0.89 KDM4E (0.40) ALDH1A1MEN1KMT2AKDM4E
SCHEMBL23911750 0.89 KDM4E (0.40) ALDH1A1MEN1KMT2AKDM4E
SCHEMBL115037 0.86 KDM4E (0.40) ALDH1A1MEN1KMT2AKDM4EPOLB
SCHEMBL16335885 0.86 KDM4E (0.40) ALDH1A1MEN1KMT2AKDM4EPOLB
SCHEMBL1760598 0.85 KDM4E (0.39) ALDH1A1MEN1KMT2AKDM4EPOLB
SCHEMBL1221875 0.83 KDM4E (0.38) ALDH1A1MEN1KMT2AKDM4E
SCHEMBL7526586 0.83 KDM4E (0.38) ALDH1A1MEN1KMT2AKDM4E
SCHEMBL4401258 0.83 KDM4E (0.38) ALDH1A1MEN1KMT2AKDM4E
SCHEMBL5701493 0.82 ALDH1A1 (0.36) ALDH1A1MEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10838302-B2 Cross-linkable fluorinated photopolymer ORTHOGONAL, INC. (US) 2020-11-17 US disclosed
US-20200301276-A1 CROSS-LINKABLE FLUORINATED PHOTOPOLYMER ORTHOGONAL, INC. (US) 2020-09-24 US disclosed
US-10739680-B2 Cross-linkable fluorinated photopolymer ORTHOGONAL, INC. (US) 2020-08-11 US disclosed
US-20190227436-A1 CROSS-LINKABLE FLUORINATED PHOTOPOLYMER ORTHOGONAL, INC. (US) 2019-07-25 US disclosed
US-20170219921-A1 PHOTOLITHOGRAPHIC PATTERNING OF DEVICES ORTHOGONAL, INC. 2017-08-03 US disclosed
US-20170222148-A1 PHOTOLITHOGRAPHIC PATTERNING OF DEVICES ORTHOGONAL, INC. 2017-08-03 US disclosed
US-9298088-B2 Fluorinated photopolymer with fluorinated sensitizer ORTHOGONAL, INC. (US) 2016-03-29 US disclosed
US-20150030982-A1 FLUORINATED PHOTOPOLYMER WITH FLUORINATED SENSITIZER ORTHOGONAL, INC. 2015-01-29 US disclosed
US-8431625-B2 Compositions curable by ring opening metathesis polymerization at low temperatures and their application in the dental field 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-04-30 US disclosed
US-8178604-B2 Solid materials obtainable by ring-opening metathesis polymerization 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-05-15 US disclosed
US-20100036015-A1 COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD 3M INNOVATIVE PROPERTIES COMPANY 2010-02-11 US disclosed
US-20090088494-A1 SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION 3M INNOVATIVE PROPERTIES COMPANY 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100036015-A1 COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD DNMT3B, HMBS, MMAB ALDH1A1 454/4885MEN1 784/4885KMT2A 1341/4885
US-20090088494-A1 SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION MMAB, DNMT3B, RHEB ALDH1A1 4132/4885MEN1 247/4885KMT2A 1609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.