Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL416791 | 0.93 | KDM4E (0.40) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL23911750 | 0.93 | KDM4E (0.40) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL7526586 | 0.90 | KDM4E (0.38) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL1221875 | 0.90 | KDM4E (0.38) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL16418948 | 0.86 | ALDH1A1 (0.36) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL29325829 | 0.86 | ALDH1A1 (0.36) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL1760598 | 0.85 | KDM4E (0.39) | KDM4EALDH1A1MEN1KMT2AHTT | |
| SCHEMBL29326148 | 0.84 | ALDH1A1 (0.35) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL29326152 | 0.84 | ALDH1A1 (0.35) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL29326136 | 0.84 | ALDH1A1 (0.35) | KDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2094760-B1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | 3M INNOVATIVE PROPERTIES CO (US) | 2017-05-31 | — | — | EP | disclosed |
| US-8431625-B2 | Compositions curable by ring opening metathesis polymerization at low temperatures and their application in the dental field | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2013-04-30 | — | — | US | disclosed |
| US-8178604-B2 | Solid materials obtainable by ring-opening metathesis polymerization | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2012-05-15 | — | — | US | disclosed |
| US-20100036015-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | 3M INNOVATIVE PROPERTIES COMPANY | 2010-02-11 | — | — | US | disclosed |
| US-20090088494-A1 | SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION | 3M INNOVATIVE PROPERTIES COMPANY | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100036015-A1 | COMPOSITIONS CURABLE BY RING OPENING METATHESIS POLYMERIZATION AT LOW TEMPERATURES AND THEIR APPLICATION IN THE DENTAL FIELD | DNMT3B, HMBS, MMAB | KDM4E 3465/4885ALDH1A1 454/4885MEN1 784/4885 |
| US-20090088494-A1 | SOLID MATERIALS OBTAINABLE BY RING-OPENING METATHESIS POLYMERIZATION | MMAB, DNMT3B, RHEB | KDM4E 1902/4885ALDH1A1 4132/4885MEN1 247/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.