Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.70 |
| ▸ | PGR | P06401 | 3/20 | 0.70 |
| ▸ | AR | P10275 | 2/20 | 0.70 |
| ▸ | SHBG | P04278 | 2/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.70 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.70 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.70 |
| ▸ | ESR1 | P03372 | 1/20 | 0.70 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.70 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.70 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.70 |
| ▸ | HRH2 | P25021 | 1/20 | 0.70 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.70 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.70 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.70 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4168654 | 1.00 | LMNA (0.70) | LMNANR3C1CYP3A4PGRAR | |
| SCHEMBL4168651 | 1.00 | LMNA (0.70) | LMNANR3C1CYP3A4PGRAR | |
| SCHEMBL571579 | 0.83 | LMNA (0.65) | LMNANR3C1CYP3A4PGRAR | |
| SCHEMBL29356176 | 0.83 | LMNA (0.70) | LMNANR3C1CYP3A4PGRAR | |
| SCHEMBL10900154 | 0.83 | LMNA (0.70) | LMNANR3C1CYP3A4PGRAR | |
| SCHEMBL10900163 | 0.83 | LMNA (0.70) | LMNANR3C1CYP3A4PGRAR | |
| Medroxyprogesterone Acetate SCHEMBL10080145 | 0.82 | NR3C1 (1.00) | LMNANR3C1CYP3A4PGRAR | |
| Medroxyprogesterone Acetate SCHEMBL4276 | 0.82 | NR3C1 (1.00) | LMNANR3C1CYP3A4PGRAR | |
| Medroxyprogesterone Acetate SCHEMBL22761990 | 0.82 | NR3C1 (1.00) | LMNANR3C1CYP3A4PGRAR | |
| Medroxyprogesterone Acetate SCHEMBL3892232 | 0.82 | NR3C1 (1.00) | LMNANR3C1CYP3A4PGRAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8580772-B2 | Combination therapies using melengestrol acetate and zilpaterol or its salts | INTERVET INC. (US) | 2013-11-12 | — | — | US | disclosed |
| US-20090181906-A1 | Combination Therapies using Melengestrol Acetate and Zilpaterol or its Salts | INTERVET INTERNATIONAL B.V. (NL) | 2009-07-16 | — | — | US | disclosed |
| US-4443377-A | Isomerization-acylation process | THE UPJOHN COMPANY (US) | 1984-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181906-A1 | Combination Therapies using Melengestrol Acetate and Zilpaterol or its Salts | MC4R, MELK, MC2R | LMNA 3026/4885NR3C1 74/4885CYP3A4 2302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.