Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 4/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 10/20 | 0.32 |
| ▸ | CNR1 | P21554 | 6/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172444 | 0.85 | CNR2 (0.32) | GCKPIK3CDCNR2CNR1RIPK1 | |
| SCHEMBL4161903 | 0.82 | CTSK (0.37) | CTSS | |
| SCHEMBL12091439 | 0.80 | PIK3CD (0.39) | GCKPIK3CDCTSD | |
| SCHEMBL12469485 | 0.78 | ALDH1A1 (0.38) | PIK3CDCTSD | |
| SCHEMBL1008853 | 0.76 | ZDHHC7 (0.39) | GCKPIK3CDCNR2CNR1CTSD | |
| SCHEMBL2297433 | 0.75 | ALDH1A1 (0.41) | PIK3CD | |
| SCHEMBL14930616 | 0.72 | CTSS (0.40) | GCKUSP30CNR2CNR1CTSS | |
| SCHEMBL13727465 | 0.70 | LIPA (0.42) | PIK3CDCNR2CNR1RIPK1 | |
| SCHEMBL4166505 | 0.68 | HPGD (0.36) | PIK3CDCNR2CNR1RIPK1 | |
| SCHEMBL14347430 | 0.68 | CNR2 (0.33) | USP30CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8236841-B2 | Fused heterocycle derivative | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20090239853-A1 | Fused heterocycle derivative | KYOWA KIRIN CO., LTD. (JP) | 2009-09-24 | — | — | US | disclosed |
| EP-2070927-A1 | FUSED HETEROCYCLIC DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239853-A1 | Fused heterocycle derivative | NR5A2, CBR3, NR3C2 | GCK 3223/4885USP30 4202/4885PIK3CD 3777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.