SCHEMBL416879

SCHEMBL416879

Nc1ccc(F)c(C(=O)O)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.61
KMT2A Q03164 4/20 0.61
ALDH1A1 P00352 4/20 0.61
CYP3A4 P08684 4/20 0.61
MAPT P10636 3/20 0.61
MEN1 O00255 3/20 0.61
TDP1 Q9NUW8 3/20 0.61
THRB P10828 2/20 0.61
RECQL P46063 2/20 0.61
MCL1 Q07820 2/20 0.61
HPGD P15428 2/20 0.61
HSD17B10 Q99714 2/20 0.61
USP2 O75604 1/20 0.61
POLB P06746 1/20 0.61
PKM P14618 1/20 0.61
APEX1 P27695 1/20 0.61
BLM P54132 1/20 0.61
TNF P01375 1/20 0.61
HSPD1 P10809 1/20 0.61
CYP2C9 P11712 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30925630 1.00 KDM4E (0.61) KDM4EKMT2AALDH1A1CYP3A4MAPT
Hydrochloric Acid SCHEMBL6984724 0.98 KMT2A (0.64) KDM4EKMT2AALDH1A1CYP3A4MAPT
SCHEMBL101125 0.83 ALDH1A1 (0.61) KDM4EKMT2AALDH1A1CYP3A4MAPT
SCHEMBL3079582 0.83 MAPT (0.49) KDM4EKMT2AALDH1A1CYP3A4MAPT
SCHEMBL30708577 0.83 ALDH1A1 (0.61) KDM4EKMT2AALDH1A1CYP3A4MAPT
SCHEMBL26972103 0.83 ALDH1A1 (0.61) KDM4EKMT2AALDH1A1CYP3A4MAPT
SCHEMBL24180500 0.81 ALDH1A1 (0.52) KDM4EKMT2AALDH1A1CYP3A4MAPT
SCHEMBL1440765 0.81 MAPT (0.44) KDM4EKMT2AALDH1A1CYP3A4MAPT
Hydrochloric Acid SCHEMBL20639113 0.81 MAPT (0.48) KDM4EKMT2AALDH1A1CYP3A4MAPT
Hydrochloric Acid SCHEMBL20639101 0.81 MAPT (0.48) KDM4EKMT2AALDH1A1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 340 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119108134-B High-flexibility and bending-resistant robot cable 浙江光大普特通讯科技股份有限公司 2025-03-25 CN claimed
CN-119108134-A High-flexibility and bending-resistant robot cable 浙江光大普特通讯科技股份有限公司 2024-12-10 CN claimed
CN-117179195-A Granulated puffed yellow croaker feed and preparation method thereof 福州海大饲料有限公司 2023-12-08 CN claimed
CN-115028986-B Cable sheath material and preparation method thereof 重庆泰山电缆有限公司 2023-06-23 CN claimed
CN-115028986-A Cable sheath material and preparation method thereof 重庆泰山电缆有限公司 2022-09-09 CN claimed
EP-1973883-B1 NOVEL COMPOUNDS AND METHODS FOR THEIR PRODUCTION BRISTOL MYERS SQUIBB CO (US) 2012-07-11 EP claimed
US-20110021481-A1 Novel Compounds and Methods for Their Production BRISTOL-MYERS SQUIBB COMPANY 2011-01-27 US claimed
CN-101578268-A Novel compounds and methods for their production BIOTICA TECH LTD (GB) 2009-11-11 CN claimed
US-20090253667-A1 18 ,21-Didesoxymacbecin Derivatives for the Treatment of Cancer BIOTICA TECHNOLOGY LIMITED (GB) 2009-10-08 US claimed
CN-101460465-A 18,21-didesoxymacbecin derivatives for the treatment of cancer BIOTICA TECH LTD (GB) 2009-06-17 CN claimed
EP-1973883-A2 NOVEL COMPOUNDS AND METHODS FOR THEIR PRODUCTION Biotica Technology Limited (GB) 2008-10-01 EP claimed
EP-1928837-A2 18,21-DIDESOXYMACBECIN DERIVATIVES FOR THE TREATMENT OF CANCER Biotica Technology Limited (GB) 2008-06-11 EP claimed
WO-2008056188-A2 NOVEL COMPOUNDS AND METHODS FOR THEIR PRODUCTION BIOTICA TECHNOLOGY LIMITED (GB) 2008-05-15 WO claimed
WO-2007128829-A2 18,21-DIDESOXYMACBECIN DERIVATIVES FOR THE TREATMENT OF CANCER BIOTICA TECHNOLOGY LIMITED (GB) 2007-11-15 WO claimed
EP-0109284-B1 6,7-DIHYDRO-5,8-DIMETHYL-9-FLUORO-1-OXO-1H,5H-BENZO(IJ)QUINOLIZINE-2-CARBOXYLIC ACID AND DERIVATIVES RIKER LABORATORIES, INC. (US) 1989-01-11 EP claimed
EP-0109284-A1 6,7-Dihydro-5,8-dimethyl-9-fluoro-1-oxo-1H,5H-benzo(ij)quinolizine-2-carboxylic acid and derivatives RIKER LABORATORIES, INC. (US) 1984-05-23 EP claimed
US-20260027106-A1 PRMT5 INHIBITORS AND USES THEREOF Epizyme, Inc. 2026-01-29 US disclosed
CN-117179195-B Granulated puffed yellow croaker feed and preparation method thereof 福州海大饲料有限公司 2025-10-31 CN disclosed
EP-0079162-A1 Derivatives of 8-amino and 8-aminomethyl benzo(ij)quinolizine RIKER LABORATORIES, INCORPORATED (US) 1983-05-18 EP disclosed
US-4380543-A BACTERICIDES RIKER LABORATORIES, INC. (US) 1983-04-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260027106-A1 PRMT5 INHIBITORS AND USES THEREOF PRMT5, PRMT1, PRMT3 KDM4E 390/4885KMT2A 155/4885ALDH1A1 3490/4885
US-20090253667-A1 18 ,21-Didesoxymacbecin Derivatives for the Treatment of Cancer BCL3, BECN1, CD22 KDM4E 1367/4885KMT2A 2175/4885ALDH1A1 2243/4885
US-20110021481-A1 Novel Compounds and Methods for Their Production BCL6, BCL3, AQP4 KDM4E 2782/4885KMT2A 3784/4885ALDH1A1 2254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.