Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 2/20 | 0.60 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.60 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 3/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MBTPS1 | Q14703 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | CTSS | P25774 | 1/20 | 0.49 |
| ▸ | CTSK | P43235 | 1/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20394533 | 1.00 | ITGA4 (0.60) | ITGA4ITGB7TRPM8TACR1ACE | |
| SCHEMBL5887603 | 0.92 | ITGA4 (0.54) | ITGA4ITGB7TRPM8TACR1ACE | |
| SCHEMBL5887605 | 0.92 | ITGA4 (0.54) | ITGA4ITGB7TRPM8TACR1ACE | |
| SCHEMBL5887764 | 0.92 | ITGA4 (0.54) | ITGA4ITGB7TRPM8TACR1ACE | |
| SCHEMBL5887767 | 0.92 | ITGA4 (0.54) | ITGA4ITGB7TRPM8TACR1ACE | |
| SCHEMBL2855310 | 0.92 | ITGA4 (0.54) | ITGA4ITGB7TRPM8TACR1ACE | |
| SCHEMBL2855306 | 0.92 | ITGA4 (0.54) | ITGA4ITGB7TRPM8TACR1ACE | |
| SCHEMBL1799032 | 0.87 | ITGA4 (0.48) | ITGA4ITGB7TRPM8TACR1POLB | |
| SCHEMBL1799033 | 0.87 | ITGA4 (0.48) | ITGA4ITGB7TRPM8TACR1POLB | |
| SCHEMBL28138481 | 0.87 | ITGA4 (0.54) | ITGA4ITGB7TACR1ACEPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11033577-B2 | Polymer conjugate of hexa-coordinated platinum complex | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2021-06-15 | — | — | US | disclosed |
| CN-108026271-B | Polymer conjugate of 6-coordinate platinum complex | 日本化药株式会社 | 2021-03-12 | — | — | CN | disclosed |
| EP-3351580-B1 | POLYMER CONJUGATE OF HEXA-COORDINATED PLATINUM COMPLEX | NIPPON KAYAKU KK (JP) | 2021-02-24 | — | — | EP | disclosed |
| US-10596191-B2 | Polymer conjugate of hexa-coordinated platinum complex | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2020-03-24 | — | — | US | disclosed |
| US-20190282612-A1 | Polymer Conjugate Of Hexa-Coordinated Platinum Complex | NIPPON KAYAKU KK (JP) | 2019-09-19 | — | — | US | disclosed |
| US-20180250332-A1 | Polymer Conjugate Of Hexa-Coordinated Platinum Complex | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2018-09-06 | — | — | US | disclosed |
| EP-3351580-A1 | POLYMER CONJUGATE OF HEXA-COORDINATED PLATINUM COMPLEX | Nippon Kayaku Kabushiki Kaisha (JP) | 2018-07-25 | — | — | EP | disclosed |
| US-8309766-B2 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | Obschestvo S. Organichennoi Otvetstvennostiyu Pharmenterprises (RU) | 2012-11-13 | — | — | US | disclosed |
| US-20090111874-A1 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | OBSCHESTVO S OGRANICHENNOI OTVETSTVENNOSTIYU PHARMENTERPRISES (RU) | 2009-04-30 | — | — | US | disclosed |
| EP-0970066-A1 | AMINOEPOXIDES FROM AMINOALDEHYDES AND IN-SITU FORMED HALOMETHYL ORGANOMETALLIC REAGENT | G.D. SEARLE & CO. (US) | 2000-01-12 | — | — | EP | disclosed |
| EP-0813519-A1 | SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-12-29 | — | — | EP | disclosed |
| EP-0804410-A1 | METHOD OF PREPARING RETROVIRAL PROTEASE INHIBITOR INTERMEDIATES | G.D. SEARLE & CO. (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1997018205-A1 | SUBSTITUTED SULFONYLALKANOYLAMINO HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1997-05-22 | — | — | WO | disclosed |
| WO-1997018190-A1 | N-PROTECTED/N-SUBSTITUTED-BETA-AMINO HYDROXY SULFONATES | G.D. SEARLE & CO. (US) | 1997-05-22 | — | — | WO | disclosed |
| EP-0762880-A1 | RETROVIRAL PROTEASE INHIBITOR COMBINATIONS | G.D. SEARLE & CO. (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5583238-A | Method for making intermediates useful in synthesis of retroviral protease inhibitors | G. D. SEARLE & CO. (US) | 1996-12-10 | — | — | US | disclosed |
| WO-1996028465-A1 | HETEROCYCLECARBONYL AMINO ACID HYDROXYETHYLAMINO SULFONAMIDE RETROVIRAL PROTEASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-09-19 | — | — | WO | disclosed |
| WO-1996022275-A1 | METHOD OF PREPARING RETROVIRAL PROTEASE INHIBITOR INTERMEDIATES | G.D. SEARLE & CO. (US) | 1996-07-25 | — | — | WO | disclosed |
| WO-1995033464-A2 | RETROVIRAL PROTEASE INHIBITOR COMBINATIONS | G.D. SEARLE & CO. (US) | 1995-12-14 | — | — | WO | disclosed |
| WO-1995006061-A1 | RETROVIRAL PROTEASE INHIBITORS AND COMBINATIONS THEREOF | G.D. SEARLE & CO. (US) | 1995-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10596191-B2 | Polymer conjugate of hexa-coordinated platinum complex | DCLRE1A, XPA, FPGS | ITGA4 3727/4885ITGB7 3225/4885TRPM8 4711/4885 |
| US-20180250332-A1 | Polymer Conjugate Of Hexa-Coordinated Platinum Complex | DCLRE1A, XPA, FPGS | ITGA4 3727/4885ITGB7 3225/4885TRPM8 4711/4885 |
| US-11033577-B2 | Polymer conjugate of hexa-coordinated platinum complex | DCLRE1A, XPA, FPGS | ITGA4 3727/4885ITGB7 3225/4885TRPM8 4711/4885 |
| US-20190282612-A1 | Polymer Conjugate Of Hexa-Coordinated Platinum Complex | DCLRE1A, XPA, FPGS | ITGA4 3727/4885ITGB7 3225/4885TRPM8 4711/4885 |
| US-20090111874-A1 | Phenyl-containing n-acyl amine and aminoacid derivatives, methods for the production thereof, a pharmaceutical composition and the use thereof | PAH, MAOA, APEH | ITGA4 3931/4885ITGB7 2893/4885TRPM8 4016/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.