SCHEMBL28138481

SCHEMBL28138481

O=C(OCc1ccccc1)[C@H](Cc1ccccc1)NCO

nearest known ligand 0.54

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ITGA4 P13612 1/20 0.54
ITGB7 P26010 1/20 0.54
TACR1 P25103 3/20 0.53
ACE P12821 1/20 0.52
POLB P06746 1/20 0.51
MBTPS1 Q14703 1/20 0.51
TYR P14679 1/20 0.50
CTSL P07711 1/20 0.49
CTSB P07858 1/20 0.49
CTSS P25774 1/20 0.49
CTSK P43235 1/20 0.49
CTRB1 P17538 2/20 0.49
ALDH1A1 P00352 3/20 0.48
ALOX15 P16050 1/20 0.48
LTA4H P09960 1/20 0.48
LAP3 P28838 1/20 0.48
MAPT P10636 1/20 0.47
S1PR1 P21453 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27604388 0.88 ITGA4 (0.52) ITGA4ITGB7TACR1ACEPOLB
SCHEMBL20394533 0.87 ITGA4 (0.60) ITGA4ITGB7TACR1ACEPOLB
SCHEMBL4169003 0.87 ITGA4 (0.60) ITGA4ITGB7TACR1ACEPOLB
SCHEMBL20394525 0.86 TACR1 (0.56) ITGA4ITGB7TACR1ACEPOLB
SCHEMBL20394526 0.86 TACR1 (0.56) ITGA4ITGB7TACR1ACEPOLB
SCHEMBL15242283 0.86 MMP8 (0.56) TACR1POLBALDH1A1
SCHEMBL19647162 0.85 ALDH1A1 (0.62) POLBALDH1A1
SCHEMBL10420650 0.85 TACR1 (0.57) ITGA4ITGB7TACR1ACEPOLB
SCHEMBL6898624 0.84 ITGA4 (0.52) ITGA4ITGB7TACR1ACEPOLB
SCHEMBL27511974 0.84 ITGA4 (0.52) ITGA4ITGB7TACR1ACEPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106566794-A A genetically engineered bacterium producing 2-phenylethanol and an applying method thereof 中国科学院微生物研究所 2017-04-19 CN disclosed