SCHEMBL4170119

SCHEMBL4170119

CCC(=O)NCC1CN(c2ccc(-c3ccc(N4CCSCC4)nc3)c(F)c2)C(=O)O1

nearest known ligand 0.58

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAOA P21397 6/20 0.58
MAOB P27338 4/20 0.58
F10 P00742 6/20 0.55
CALML3 P27482 4/20 0.49
CYP2C19 P33261 2/20 0.49
CYP3A4 P08684 1/20 0.49
CYP2C9 P11712 1/20 0.48
LMNA P02545 1/20 0.47
PTGS1 P23219 1/20 0.47
SDHA P31040 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4170115 1.00 MAOA (0.58) MAOAMAOBF10CALML3CYP2C19
SCHEMBL4160241 0.92 MAOA (0.70) MAOAMAOBF10CALML3CYP2C19
SCHEMBL4160239 0.92 MAOA (0.70) MAOAMAOBF10CALML3CYP2C19
SCHEMBL4168138 0.91 MAOA (0.58) MAOAMAOBF10CALML3CYP2C19
SCHEMBL4168134 0.91 MAOA (0.58) MAOAMAOBF10CALML3CYP2C19
SCHEMBL4181421 0.90 F10 (0.55) MAOAMAOBF10CALML3CYP2C19
SCHEMBL4181426 0.90 F10 (0.55) MAOAMAOBF10CALML3CYP2C19
SCHEMBL4173633 0.86 MAOA (0.52) MAOAMAOBF10CALML3CYP2C19
SCHEMBL4173639 0.86 MAOA (0.52) MAOAMAOBF10CALML3CYP2C19
SCHEMBL4708190 0.83 MAOA (0.66) MAOAMAOBF10CALML3LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090018123-A1 Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation SINDKHEDKAR MILIND D 2009-01-15 US claimed
EP-1912980-A2 OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION Wockhardt Limited (IN) 2008-04-23 EP claimed
WO-2007023507-A2 OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION WOCKHARDT LIMITED (IN) 2007-03-01 WO claimed
US-20090018123-A1 Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation SINDKHEDKAR MILIND D 2009-01-15 US disclosed
EP-1912980-A2 OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION Wockhardt Limited (IN) 2008-04-23 EP disclosed
WO-2007023507-A2 OXAZOLIDINONES BEARING ANTIMICROBIAL ACTIVITY COMPOSITION AND METHODS OF PREPARATION WOCKHARDT LIMITED (IN) 2007-03-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090018123-A1 Oxazolidinones Bearing Antimicrobial Activity Composition and Methods of Preparation POLL, POLM, POLRMT MAOA 3788/4885MAOB 3240/4885F10 2299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.