Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WDR5 | P61964 | 1/20 | 0.59 |
| ▸ | LDHA | P00338 | 1/20 | 0.58 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.51 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | GLA | P06280 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | CDC25B | P30305 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.44 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535161 | 0.86 | NCEH1 (0.51) | WDR5LDHANCEH1ALDH1A1HPGD | |
| SCHEMBL29625682 | 0.85 | WDR5 (0.63) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL23515379 | 0.85 | WDR5 (0.63) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL3933696 | 0.85 | GPR35 (0.46) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL11594011 | 0.84 | NCEH1 (0.50) | WDR5LDHANCEH1POLBALDH1A1 | |
| SCHEMBL25799004 | 0.84 | NCEH1 (0.50) | WDR5LDHANCEH1POLBALDH1A1 | |
| SCHEMBL10422778 | 0.84 | WDR5 (0.61) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL14150812 | 0.83 | NCEH1 (0.56) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL28150825 | 0.83 | WDR5 (0.56) | WDR5LDHANR4A1NR4A2NR4A3 | |
| SCHEMBL11115871 | 0.82 | WDR5 (0.51) | WDR5LDHANR4A1NR4A2NR4A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107019687-A | The purposes of the naphthalenecarboxamide class compound of N (4 chlorphenyl) 3 hydroxyl 2 | 上海市伤骨科研究所 | 2017-08-08 | — | — | CN | disclosed |
| CN-102964224-B | The alkoxyalkyl method of aromatic substrate | DAVID PROCESS TECHNOLOGY LTD. (GB) | 2016-05-04 | — | — | CN | disclosed |
| CN-102964224-A | Process | DAVY PROCESS TECHN LTD | 2013-03-13 | — | — | CN | disclosed |
| CN-102958892-A | Method for preparing chemical compounds of interest by aromatic nucleophilic substitution | CENTRE NAT RECH SCIENT | 2013-03-06 | — | — | CN | disclosed |
| US-20120316337-A1 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP | UNIVERSITE DU MAINE (FR) | 2012-12-13 | — | — | US | disclosed |
| US-20120316337-A1 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP | UNIVERSITE DU MAINE (FR) | 2012-12-13 | — | — | US | disclosed |
| US-20120316337-A1 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP | UNIVERSITE DU MAINE (FR) | 2012-12-13 | — | — | US | disclosed |
| CN-101203475-B | Method of producing a composite material | DAVY PROCESS TECHN LTD | 2012-06-20 | — | — | CN | disclosed |
| CN-101560272-A | Olefinic polymerization catalyst, preparation method and polymerization method | YINGKOU XIANGYANG CATALYST CO (CN) | 2009-10-21 | — | — | CN | disclosed |
| US-20090215978-A1 | PROCESS | DAVY PROCESS TECHNOLOGY LIMITED (GB) | 2009-08-27 | — | — | US | disclosed |
| CN-101203475-A | method | DAVY PROCESS TECHN LTD (GB) | 2008-06-18 | — | — | CN | disclosed |
| EP-1853540-A1 | PROCESS | Davy Process Technology Limited (GB) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006089900-A1 | PROCESS | DAVY PROCESS TECHNOLOGY LTD (GB) | 2006-08-31 | — | — | WO | disclosed |
| US-4123219-A | PHOTOCHEMICAL DIMERIZATION OF TWO NAPHTHALENE COMPOUNDS AND HEATING PRODUCT TO RELEASE ENERGY AS HEAT | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH (AU) | 1978-10-31 | — | — | US | disclosed |
| US-3994675-A | Chemical storage of radiant energy | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANIZATION (AU) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120316337-A1 | METHOD FOR PREPARING CHEMICAL COMPOUNDS OF INTEREST BY NUCLEOPHILIC AROMATIC SUBSTITUTION OF AROMATIC CARBOXYLIC ACID DERIVATIVES SUPPORTING AT LEAST ONE ELECTRO-ATTRACTIVE GROUP | COMT, NAA15, NUDC | WDR5 3436/4885LDHA 2726/4885NR4A1 775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.