Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCEH1 | Q6PIU2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | WDR5 | P61964 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4170309 | 0.86 | WDR5 (0.59) | NCEH1ALDH1A1HPGDWDR5HSD17B10 | |
| SCHEMBL8580920 | 0.84 | ALDH1A1 (0.45) | NCEH1ALDH1A1HPGDMAPTWDR5 | |
| SCHEMBL25799004 | 0.84 | NCEH1 (0.50) | NCEH1ALDH1A1HPGDMAPTWDR5 | |
| SCHEMBL11594011 | 0.84 | NCEH1 (0.50) | NCEH1ALDH1A1HPGDMAPTWDR5 | |
| SCHEMBL21569594 | 0.83 | NCEH1 (0.56) | NCEH1ALDH1A1HPGDMAPTWDR5 | |
| SCHEMBL4664908 | 0.83 | ALDH1A1 (0.63) | ALDH1A1HPGDMAPTWDR5MAOB | |
| SCHEMBL5039147 | 0.82 | NCEH1 (0.44) | NCEH1ALDH1A1HPGDMAPTWDR5 | |
| SCHEMBL15636146 | 0.81 | LMNA (0.50) | ALDH1A1HPGDMAPTWDR5HSD17B10 | |
| SCHEMBL11802841 | 0.80 | NCEH1 (0.50) | NCEH1ALDH1A1HPGDMAPTWDR5 | |
| SCHEMBL28006860 | 0.80 | CDC25B (0.60) | NCEH1ALDH1A1HPGDMAOBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116917450-A | Treatment composition comprising plant rosin material | 宝洁公司 | 2023-10-20 | — | — | CN | disclosed |
| US-9884830-B2 | Synthesis of tetracyclines and analogues thereof | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-02-06 | — | — | US | disclosed |
| US-20160340325-A1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2016-11-24 | — | — | US | disclosed |
| US-20140163238-A1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-06-12 | — | — | US | disclosed |
| US-20090131299-A1 | 3-Methylbenzyl-Isobutyrate | SYMRISE GMBH & CO. KG (DE) | 2009-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140163238-A1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | TET1, TET3, MYC | NCEH1 3000/4885ALDH1A1 4455/4885HPGD 3373/4885 |
| US-20090131299-A1 | 3-Methylbenzyl-Isobutyrate | ABAT, GABRB3, GABBR1 | NCEH1 1253/4885ALDH1A1 141/4885HPGD 2203/4885 |
| US-20160340325-A1 | SYNTHESIS OF TETRACYCLINES AND ANALOGUES THEREOF | TET1, TET3, MYC | NCEH1 3000/4885ALDH1A1 4455/4885HPGD 3373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.