Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Pirenzepine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 2/20 | 0.98 |
| ▸ | LMNA | P02545 | 2/20 | 1.00 |
| ▸ | GMNN | O75496 | 1/20 | 1.00 |
| ▸ | APEX1 | P27695 | 1/20 | 1.00 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.98 |
| ▸ | USP2 | O75604 | 1/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.98 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.98 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.98 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.98 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.98 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.98 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pirenzepine SCHEMBL1462692 | 1.00 | LMNA (1.00) | LMNAGMNNAPEX1CHRM2CHRM1 | |
| Pirenzepine SCHEMBL30548470 | 1.00 | LMNA (1.00) | LMNAGMNNAPEX1CHRM2CHRM1 | |
| Pirenzepine SCHEMBL7985618 | 0.99 | LMNA (0.98) | LMNAGMNNAPEX1CHRM2CHRM1 | |
| Pirenzepine SCHEMBL5987941 | 0.99 | LMNA (0.98) | LMNAGMNNAPEX1CHRM2CHRM1 | |
| Pirenzepine SCHEMBL11415337 | 0.99 | LMNA (0.98) | LMNAGMNNAPEX1CHRM2CHRM1 | |
| Pirenzepine SCHEMBL30553045 | 0.99 | LMNA (1.00) | LMNAGMNNAPEX1CHRM2CHRM1 | |
| Pirenzepine SCHEMBL29793172 | 0.99 | LMNA (1.00) | LMNAGMNNAPEX1CHRM2CHRM1 | |
| Pirenzepine SCHEMBL9254860 | 0.99 | LMNA (1.00) | LMNAGMNNAPEX1CHRM2CHRM1 | |
| Pirenzepine SCHEMBL41705 | 0.99 | LMNA (1.00) | LMNAGMNNAPEX1CHRM2CHRM1 | |
| Pirenzepine SCHEMBL15300969 | 0.98 | LMNA (0.98) | LMNAGMNNAPEX1CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3317 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4739777-A1 | TRANSMISSIBLE ELEMENTS COMPRISING PATHWAY MODIFICATION SYSTEMS AND EXOGENOUS NUCLEIC ACIDS FOR THE PRODUCTION OF MOLECULES OF INTEREST | SNIPR Biome ApS (DK) | 2026-05-13 | — | — | EP | claimed |
| US-20250223564-A1 | HYPOIMMUNE BETA CELLS DIFFERENTIATED FROM PLURIPOTENT STEM CELLS AND RELATED USES AND METHODS | SANA BIOTECHNOLOGY, INC. | 2025-07-10 | — | — | US | claimed |
| EP-4574980-A2 | A NOVEL TYPE OF CRISPR/CAS SYSTEM | SNIPR Biome ApS (DK) | 2025-06-25 | — | — | EP | claimed |
| CN-120153077-A | Novel CRISPR/Cas system | 斯尼普生物群系有限公司 | 2025-06-13 | — | — | CN | claimed |
| US-20250101382-A1 | GENETICALLY MODIFIED CELLS AND COMPOSITIONS AND USES THEREOF | SANA BIOTECHNOLOGY, INC. (US) | 2025-03-27 | — | — | US | claimed |
| WO-2025054202-A1 | METHOD OF SCREENING A SAMPLE COMPRISING A TRANSGENE WITH A UNIQUE BARCODE | SANA BIOTECHNOLOGY, INC. (US) | 2025-03-13 | — | — | WO | claimed |
| US-20250083864-A1 | PROGRESSIVE DIE MANUFACTURING METHOD AND ASSOCIATED TOOLING ASSEMBLIES FOR ERGONOMIC PULL TABS | INTELLECTUAL CAPITAL MANAGEMENT (US) | 2025-03-13 | — | — | US | claimed |
| WO-2025008424-A1 | TRANSMISSIBLE ELEMENTS COMPRISING PATHWAY MODIFICATION SYSTEMS AND EXOGENOUS NUCLEIC ACIDS FOR THE PRODUCTION OF MOLECULES OF INTEREST | SNIPR BIOME APS (DK) | 2025-01-09 | — | — | WO | claimed |
| EP-4479416-A1 | ENGINEERED CD47 PROTEINS AND USES THEREOF | Sana Biotechnology, Inc. (US) | 2024-12-25 | — | — | EP | claimed |
| CN-119032102-A | Engineered CD47 proteins and uses thereof | 萨那生物技术股份有限公司 | 2024-11-26 | — | — | CN | claimed |
| EP-0100414-A2 | Beverage dispenser | CADBURY SCHWEPPES PLC (GB) | 1984-02-15 | — | — | EP | claimed |
| EP-0099846-A1 | Improvements in diaper fastener tabs and tape stock for diaper fastener tabs | Zervoudakis, John (GR) | 1984-02-01 | — | — | EP | claimed |
| US-4288958-A | Horizontal siding panel system with vertical stringers | ALCAN ALUMINUM CORPORATION (US) | 1981-09-15 | — | — | US | claimed |
| US-4286808-A | Snap-in tee connector | HANCOR, INC. (US) | 1981-09-01 | — | — | US | claimed |
| US-4246714-A | Multi-sided display device | ROTHCHILD PRINTING COMPANY, INC. (US) | 1981-01-27 | — | — | US | claimed |
| EP-0022589-A2 | A package for use in a beverage dispenser | Cadbury Schweppes Limited (GB) | 1981-01-21 | — | — | EP | claimed |
| US-4230150-A | Tilting disc check valve | SCARAMUCCI, JOHN P. | 1980-10-28 | — | — | US | claimed |
| EP-0002391-A1 | Crash-bottom carton and blank therefor | DRG (UK) LIMITED (GB) | 1979-06-13 | — | — | EP | claimed |
| EP-0001626-A1 | Injection blow molding apparatus method | ETHYL CORPORATION (US) | 1979-05-02 | — | — | EP | claimed |
| US-4102233-A | Upright harpsichord action | KERN EVAN J | 1978-07-25 | — | — | US | claimed |