Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12825059 | 0.85 | CYP3A4 (0.31) | CYP3A4SLC7A5CYP1A2 | |
| SCHEMBL12825056 | 0.85 | CYP3A4 (0.31) | CYP3A4SLC7A5CYP1A2 | |
| SCHEMBL10240652 | 0.85 | CYP3A4 (0.31) | CYP3A4SLC7A5CYP1A2 | |
| Histidine SCHEMBL27446195 | 0.85 | SLC7A5 (0.46) | CYP3A4SLC7A5CYP1A2 | |
| Histidine SCHEMBL3258 | 0.83 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2 | |
| Histidine SCHEMBL3259 | 0.83 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2 | |
| Histidine SCHEMBL8080341 | 0.83 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2 | |
| Histidine SCHEMBL388563 | 0.83 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2 | |
| Histidine SCHEMBL163442 | 0.83 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2 | |
| Histidine SCHEMBL18824897 | 0.83 | SLC7A5 (0.47) | CYP3A4SLC7A5CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | CANNIZZARO CARINA | 2009-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090247488-A1 | ANTI-INFLAMMATORY PHOSPHONATE COMPOUNDS | PHOSPHO1, TNF, PTGES | CYP3A4 1894/4885SLC7A5 4058/4885CYP1A2 3531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.