Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27686311 | 0.83 | GABRA1 (0.35) | GABRA1GABRB2POLB | |
| SCHEMBL4053225 | 0.79 | — | — | |
| SCHEMBL11441284 | 0.78 | GABRA1 (0.41) | GABRA1GABRB2KDM4E | |
| SCHEMBL1491968 | 0.75 | — | — | |
| SCHEMBL8718496 | 0.74 | GABRA1 (0.48) | GABRA1GABRB2POLBKDM4E | |
| SCHEMBL27835308 | 0.73 | — | — | |
| SCHEMBL1655686 | 0.72 | GABRA1 (0.36) | GABRA1GABRB2POLB | |
| SCHEMBL7613712 | 0.72 | CHEK1 (0.37) | — | |
| SCHEMBL14560346 | 0.72 | SRC (0.43) | GABRA1GABRB2POLBKDM4E | |
| SCHEMBL9225445 | 0.72 | GPR84 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113683546-A | Alkyl pyrrole aldehyde derivative and preparation method and application thereof | 厦门医学院 | 2021-11-23 | — | — | CN | disclosed |
| CN-113683546-A | Alkyl pyrrole aldehyde derivative and preparation method and application thereof | 厦门医学院 | 2021-11-23 | — | — | CN | disclosed |
| CN-109467558-B | 1-hydropyrrolizine derivative and synthesis method and application thereof | 广西师范大学 | 2021-03-23 | — | — | CN | disclosed |
| WO-2009084007-A1 | PYRROLE END-CAPPED BIPYRIDINE ASSAY POWDER FOR SELECTIVE DETECTION OF ZINC IONS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-07-09 | — | — | WO | disclosed |
| US-6441194-B1 | TWO STEP, ONE POT ALKYLATION IN PRESENCE OF BRONSTEAD ACID CATALYST; REACTING PYRROLE-2-CARBALDEHYDE WITH VILSMEIR REAGENT, SUCH AS OXALYL CHLORIDE AND DIMETHYLFORAMIDE, THEN ALKYLATING AGENT, SUCH AS TERTBUTYL CHORIDE | EMORY UNIVERSITY | 2002-08-27 | — | — | US | disclosed |
| WO-2001028997-A2 | SYNTHESIS OF 4-SUBSTITUTED PYRROLE-2-CARBALDEHYDE COMPOUNDS | EMORY UNIVERSITY (US) | 2001-04-26 | — | — | WO | disclosed |