Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | PRKCI | P41743 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7086196 | 0.87 | GPR84 (0.45) | GPR84HIF1AEPAS1 | |
| SCHEMBL28740087 | 0.85 | GPR84 (0.47) | GPR84HIF1AEPAS1 | |
| SCHEMBL4688286 | 0.82 | GPR84 (0.31) | GPR84 | |
| SCHEMBL7613712 | 0.80 | CHEK1 (0.37) | — | |
| SCHEMBL1491968 | 0.75 | — | — | |
| SCHEMBL9625138 | 0.74 | PRKCI (0.43) | GPR84ELANEPRKCI | |
| SCHEMBL29851040 | 0.72 | RAB9A (0.38) | GPR84ELANE | |
| SCHEMBL10538542 | 0.72 | GPR84 (0.34) | GPR84PRKCI | |
| SCHEMBL28117526 | 0.70 | GPR84 (0.37) | GPR84ELANE | |
| SCHEMBL27763230 | 0.70 | GPR84 (0.33) | GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591355-A4 | PORPHYCENE COMPOUNDS FOR PHOTODYNAMIC THERAPY. | CYTOPHARM INC (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0591355-A1 | PORPHYCENE COMPOUNDS FOR PHOTODYNAMIC THERAPY | CYTOPHARM, INC. (US) | 1994-04-13 | — | — | EP | disclosed |
| WO-1993000087-A1 | PORPHYCENE COMPOUNDS FOR PHOTODYNAMIC THERAPY | CYTOPHARM, INC. (US) | 1993-01-07 | — | — | WO | disclosed |