Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30523855 | 0.77 | ALDH1A1 (0.52) | ALDH1A1MAPTHSP90AA1KDM4EHSP90AB1 | |
| SCHEMBL7027758 | 0.76 | DYRK1A (0.57) | ALDH1A1MAPTHSP90AA1KDM4EHSP90AB1 | |
| SCHEMBL30112896 | 0.75 | CLK1 (0.43) | ALDH1A1PDPK1HSP90AA1KDM4EDYRK1A | |
| SCHEMBL19044349 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MAPTHSP90AA1KDM4EHSP90AB1 | |
| SCHEMBL2269742 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4ESMN1; SMN2MET | |
| SCHEMBL11024480 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MAPTHSP90AA1KDM4EHSP90AB1 | |
| SCHEMBL15638042 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MAPTHSP90AA1KDM4EHSP90AB1 | |
| SCHEMBL3952706 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MAPTHSP90AA1KDM4EHSP90AB1 | |
| SCHEMBL31029246 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MAPTHSP90AA1KDM4EHSP90AB1 | |
| SCHEMBL31391337 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4ECYP3A4PRMT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 187 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240336606-A1 | SUBSTITUTED BENZO OR PYRIDOPYRIMIDINE AMINE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | SHANGHAI ZELGEN PHARMA.TECH CO., LTD. (CN) | 2024-10-10 | — | — | US | claimed |
| EP-4234548-A1 | SUBSTITUTED BENZO OR PYRIDOPYRIMIDINE AMINE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Suzhou Zelgen Biopharmaceutical Co., Ltd. (CN) | 2023-08-30 | — | — | EP | claimed |
| CN-112457309-B | Phenyl-substituted pyrido-pyrimidinamine compound and application thereof as antibacterial drug | 扬州工业职业技术学院 | 2023-03-17 | — | — | CN | claimed |
| CN-115611865-A | Substituted benzo or pyrido pyrimidine amine inhibitor and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2023-01-17 | — | — | CN | claimed |
| CN-114907324-A | Substituted benzo or pyrido pyrimidine amine inhibitor and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2022-08-16 | — | — | CN | claimed |
| WO-2022083657-A1 | SUBSTITUTED BENZO OR PYRIDOPYRIMIDINE AMINE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 苏州泽璟生物制药股份有限公司 | 2022-04-28 | — | — | WO | claimed |
| CN-114380805-A | Substituted benzo or pyrido pyrimidine amine inhibitor and preparation method and application thereof | 苏州泽璟生物制药股份有限公司 | 2022-04-22 | — | — | CN | claimed |
| CN-112457309-A | Phenyl-substituted pyrido-pyrimidinamine compound and application thereof as antibacterial drug | 扬州工业职业技术学院 | 2021-03-09 | — | — | CN | claimed |
| US-20120178180-A1 | METHODS FOR THE IDENTIFICATION OF ZAP-70 INTERACTING MOLECULES AND FOR THE PURIFICATION OF ZAP-70 | CELLZOME GMBH (DE) | 2012-07-12 | — | — | US | claimed |
| EP-1730124-A4 | CERTAIN TRIAZOLE-BASED COMPOUNDS, COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORP (US) | 2009-04-01 | — | — | EP | claimed |
| WO-2007137867-A1 | METHODS FOR THE IDENTIFICATION OF ZAP-70 INTERACTING MOLECULES AND FOR THE PURIFICATION OF ZAP-70 | CELLZOME AG (DE) | 2007-12-06 | — | — | WO | claimed |
| EP-1862802-A1 | Methods for the identification of ZAP-70 interacting molecules and for the purification of ZAP-70 | CELLZOME AG (DE) | 2007-12-05 | — | — | EP | claimed |
| EP-1730124-A1 | CERTAIN TRIAZOLE-BASED COMPOUNDS, COMPOSITIONS, AND USES THEREOF | Amphora Discovery Corporation (US) | 2006-12-13 | — | — | EP | claimed |
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | claimed |
| WO-2005097758-A1 | CERTAIN TRIAZOLE-BASED COMPOUNDS, COMPOSITIONS, AND USES THEREOF | AMPHORA DISCOVERY CORPORATION (US) | 2005-10-20 | — | — | WO | claimed |
| US-20250325572-A1 | TREATMENTS FOR PAIN | SEVENLESS THERAPEUTICS LTD (GB) | 2025-10-23 | — | — | US | disclosed |
| EP-4598538-A1 | NEW TREATMENTS FOR PAIN | Sevenless Therapeutics Limited (GB) | 2025-08-13 | — | — | EP | disclosed |
| WO-1996034867-A1 | PYRIDO[2,3-d]PYRIMIDINES FOR INHIBITING PROTEIN TYROSINE KINASE MEDIATED CELLULAR PROLIFERATION | WARNER-LAMBERT COMPANY (US) | 1996-11-07 | — | — | WO | disclosed |
| WO-1996015128-A2 | 6-ARYL PYRIDO[2,3-d]PYRIMIDINES AND NAPHTHYRIDINES FOR INHIBITING PROTEIN TYROSINE KINASE MEDIATED CELLULAR PROLIFERATION | WARNER-LAMBERT COMPANY (US) | 1996-05-23 | — | — | WO | disclosed |
| CN-87103904-A | Weedicide | — | 1988-02-10 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240336606-A1 | SUBSTITUTED BENZO OR PYRIDOPYRIMIDINE AMINE INHIBITOR, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | WEE1, SOS1, WEE2 | ALDH1A1 637/4885PDPK1 517/4885MAPT 4191/4885 |
| US-20250325572-A1 | TREATMENTS FOR PAIN | OPRL1, ACHE, OPRK1 | ALDH1A1 1092/4885PDPK1 3680/4885MAPT 851/4885 |
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ALDH1A1 720/4885PDPK1 2307/4885MAPT 2111/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.