SCHEMBL4171307

SCHEMBL4171307

C[SiH2]OC(Cc1ccccc1)c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 3/20 0.42
TAAR1 Q96RJ0 5/20 0.41
SLC6A2 P23975 4/20 0.41
SLC6A4 P31645 3/20 0.41
SLC6A3 Q01959 3/20 0.41
MAOA P21397 1/20 0.41
CYP2A6 P11509 1/20 0.41
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
EPHX1 P07099 2/20 0.39
ADRB2 P07550 1/20 0.39
ADRB1 P08588 1/20 0.39
HTR1A P08908 1/20 0.39
ADORA3 P0DMS8 1/20 0.39
DRD2 P14416 1/20 0.39
ADRA2B P18089 1/20 0.39
ADRA2C P18825 1/20 0.39
CNR1 P21554 1/20 0.39
HTR2A P28223 1/20 0.39
MC4R P32245 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5023592 0.88 SOAT1 (0.41) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL5024553 0.84 MAOB (0.45) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL29066974 0.81 SIGMAR1 (0.40) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL28662648 0.81 SIGMAR1 (0.43) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL705910 0.81 SLC6A2 (0.40) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL704840 0.81 SLC6A2 (0.40) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL703380 0.81 SLC6A2 (0.40) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL9499341 0.81 SLC6A2 (0.40) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL3894504 0.81 EPHX1 (0.43) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL23910518 0.80 SIGMAR1 (0.39) SIGMAR1TAAR1SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119552510-A High-refractive-index low-haze addition type liquid silicone rubber and preparation method thereof 湖北兴瑞硅材料有限公司 2025-03-04 CN claimed
CN-115181223-B Low-gloss matte auxiliary agent, preparation method thereof and molded body 铨盛聚碳科技股份有限公司 2023-08-29 CN claimed
EP-3674339-B1 RESIN COMPOSITION LG CHEMICAL LTD (KR) 2023-06-28 EP claimed
CN-114456385-B Preparation method of MDT type methylphenyl silicone oil for cosmetics 湖南科技学院 2023-04-21 CN claimed
CN-114456385-A Preparation method of MDT (methyl phenyl silicone oil) for cosmetics 湖南科技学院 2022-05-10 CN claimed
CN-118580825-A Primer-free two-component polyurethane adhesive 伊利诺斯工具制品有限公司 2024-09-03 CN disclosed
CN-117004360-A Two-component adhesive composition suitable for priming-free substrates PPG涂料(天津)有限公司 2023-11-07 CN disclosed
CN-114456385-B Preparation method of MDT type methylphenyl silicone oil for cosmetics 湖南科技学院 2023-04-21 CN disclosed
CN-115181223-A Low-gloss matte auxiliary agent, preparation method thereof and formed body 铨盛聚碳科技股份有限公司 2022-10-14 CN disclosed
CN-112194744-A Hydrogenated cycloolefin polymer and preparation method thereof 广东新华粤石化集团股份公司 2021-01-08 CN disclosed
CN-106366107-B A kind of synthetic method of diffusion pump oil 中昊晨光化工研究院有限公司 2019-02-19 CN disclosed
CN-105585956-B Solvent-type organosilicon impregnating varnish and its preparation method and application 株洲时代新材料科技股份有限公司 2018-02-02 CN disclosed
CN-105585957-B Silicone impregnating varnish and its preparation method and application 株洲时代新材料科技股份有限公司 2017-12-15 CN disclosed
CN-106366107-A Diffusion pump oil synthesis method 中昊晨光化工研究院有限公司 2017-02-01 CN disclosed
US-20090167164-A1 GAS BARRIER FILM, RESIN BASE FOR ORGANIC ELECTROLUMINESCENT DEVICE, ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME, AND METHOD FOR PRODUCING GAS BARRIER FILM KONICA MINOLTA HOLDINGS, INC. (JP) 2009-07-02 US disclosed