SCHEMBL5023592

SCHEMBL5023592

C[SiH2]OC(Cc1ccc(N)cc1)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 1/20 0.41
MAOB P27338 5/20 0.40
MAOA P21397 4/20 0.40
PDE4A P27815 1/20 0.38
F2 P00734 2/20 0.36
PRSS1 P07477 1/20 0.36
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36
SLC6A4 P31645 2/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNA4 P43681 1/20 0.36
SLC6A2 P23975 2/20 0.35
TAAR1 Q96RJ0 2/20 0.35
SLC6A3 Q01959 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
CYP2A6 P11509 1/20 0.35
ADORA2A P29274 1/20 0.35
ADORA1 P30542 1/20 0.35
GAA P10253 1/20 0.35
MAPT P10636 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4171307 0.88 SIGMAR1 (0.42) MAOASLC6A4SLC6A2TAAR1SLC6A3
SCHEMBL5024553 0.83 MAOB (0.45) MAOBMAOASLC6A4SLC6A2TAAR1
SCHEMBL14137752 0.81 SOAT1 (0.44) SOAT1MAOBMAOAPDE4AF2
SCHEMBL5023948 0.77 IDO1 (0.33) SLC6A4CHRNB2CHRNA4TAAR1SIGMAR1
SCHEMBL27608757 0.74 SOAT1 (0.51) SOAT1RAB9ANPC1SMN1; SMN2
SCHEMBL3894504 0.74 EPHX1 (0.43) MAOASLC6A4CHRNB2CHRNA4SLC6A2
SCHEMBL704840 0.74 SLC6A2 (0.40) MAOASLC6A4SLC6A2TAAR1SLC6A3
SCHEMBL28883509 0.72 SIGMAR1 (0.38) MAOASLC6A4SLC6A2TAAR1SLC6A3
SCHEMBL8732205 0.72 TAAR1 (0.52) SOAT1MAOBMAOARAB9ANPC1
SCHEMBL28662648 0.71 SIGMAR1 (0.43) MAOASLC6A4SLC6A2TAAR1SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240274848-A1 FLUORINATED IONOMERS, POLYMER ELECTROLYTE MEMBRANES, FUEL CELLS, AND METHODS COLORADO SCHOOL OF MINES 2024-08-15 US disclosed
US-9240287-B2 Immobilized heteropoly acids and the use of the same electrode stabilization and enhancement COLORADO SCHOOL OF MINES (US) 2016-01-19 US disclosed
US-20140234750-A1 IMMOBILIZED HETEROPOLY ACIDS AND THE USE OF THE SAME FOR ELECTRODE STABILIZATION AND ENHANCEMENT COLORADO SCHOOL OF MINES (US) 2014-08-21 US disclosed
US-8753997-B2 Immobilized heteropoly acids and the use of the same for electrode stabilization and enhancement COLORADO SCHOOL OF MINES (US) 2014-06-17 US disclosed
US-20080299433-A1 IMMOBILIZED HETEROPOLY ACIDS AND THE USE OF THE SAME FOR ELECTRODE STABILIZATION AND ENHANCEMENT COLORADO SCHOOL OF MINES 2008-12-04 US disclosed