Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 7/20 | 0.42 |
| ▸ | CES1 | P23141 | 7/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27578934 | 0.80 | CES2 (0.50) | CES2CES1PPARA | |
| Ammonia Solution, Strong SCHEMBL5962258 | 0.79 | CES2 (0.49) | CES2CES1PPARA | |
| Ammonia Solution, Strong SCHEMBL22518255 | 0.79 | CES2 (0.49) | CES2CES1PPARA | |
| Ammonia Solution, Strong SCHEMBL28814751 | 0.79 | CES2 (0.46) | CES2CES1CNR2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL3176477 | 0.78 | CES2 (0.48) | CES2CES1PPARA | |
| Hydrochloric Acid SCHEMBL27574011 | 0.77 | CES2 (0.45) | CES2CES1CNR2ALDH1A1MAPT | |
| SCHEMBL27704454 | 0.77 | CYP1A2 (0.53) | CES1CNR2CNR1DRD2PPARA | |
| SCHEMBL31631736 | 0.76 | CES2 (0.53) | CES2CES1PPARA | |
| SCHEMBL31299650 | 0.75 | CNR2 (0.46) | CNR2CNR1PPARACYP1A2ALDH1A1 | |
| SCHEMBL27684778 | 0.75 | CNR2 (0.46) | CNR2CNR1PPARACYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101517008-B | Polymeric hair dyes | CIBA HOLDING INC | 2014-03-19 | — | — | CN | disclosed |
| US-8268014-B2 | Hair dyeing composition | BASF SE Ludwigshafen (DE) | 2012-09-18 | — | — | US | disclosed |
| US-20120017931-A1 | HAIR DYEING COMPOSITION | BASF SE (DE) | 2012-01-26 | — | — | US | disclosed |
| EP-2044158-B1 | POLYMERIC HAIR DYES | BASF SE (DE) | 2011-11-23 | — | — | EP | disclosed |
| US-7731761-B2 | Polymeric hair dyes | CIBA CORPORATION (US) | 2010-06-08 | — | — | US | disclosed |
| US-20090255063-A1 | Polymeric hair dyes | CIBA CORP. | 2009-10-15 | — | — | US | disclosed |
| CN-101517008-A | Polymeric hair dyes | CIBA SC HOLDING AG (CH) | 2009-08-26 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120017931-A1 | HAIR DYEING COMPOSITION | CYB5R3, CYC1, CYCS | CES2 679/4885CES1 2032/4885CNR2 325/4885 |
| US-20090255063-A1 | Polymeric hair dyes | SCO2, CYB5R3, OR10J3 | CES2 702/4885CES1 1691/4885CNR2 123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.