Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 11/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 11/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 11/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 11/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 11/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 11/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 11/20 | 0.39 |
| ▸ | F7 | P08709 | 1/20 | 0.35 |
| ▸ | F3 | P13726 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.34 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.34 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.34 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.34 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4165083 | 0.87 | CSNK2A2 (0.34) | CSNK2A2CSNK2BCSNK2A1PRKAB2PRKAG1 | |
| SCHEMBL3254879 | 0.86 | PRKAG1 (0.40) | CSNK2A2CSNK2BCSNK2A1PRKAB2PRKAG1 | |
| SCHEMBL3247067 | 0.81 | CSNK2A2 (0.43) | CSNK2A2CSNK2BCSNK2A1PRKAB2PRKAG1 | |
| SCHEMBL3244399 | 0.81 | GAA (0.41) | CSNK2A2CSNK2BCSNK2A1PRKAB2PRKAG1 | |
| SCHEMBL3244394 | 0.81 | BCL2L1 (0.39) | CSNK2A2CSNK2BCSNK2A1PRKAB2PRKAG1 | |
| SCHEMBL3253927 | 0.80 | CSNK2A2 (0.33) | CSNK2A2CSNK2BCSNK2A1PRKAB2PRKAG1 | |
| SCHEMBL3253930 | 0.80 | CSNK2A2 (0.33) | CSNK2A2CSNK2BCSNK2A1PRKAB2PRKAG1 | |
| SCHEMBL4169304 | 0.80 | HSD17B10 (0.41) | CSNK2A2CSNK2BCSNK2A1F7F3 | |
| Hydrochloric Acid SCHEMBL3250727 | 0.79 | CSNK2A2 (0.32) | CSNK2A2CSNK2BCSNK2A1PRKAB2PRKAG1 | |
| Hydrochloric Acid SCHEMBL3250722 | 0.79 | CSNK2A2 (0.32) | CSNK2A2CSNK2BCSNK2A1PRKAB2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426437-B2 | Pyrroloquinoline derivatives and their use as protein kinases inhibitors | PIERRE FABRE MEDICAMENT (FR) | 2013-04-23 | — | — | US | disclosed |
| US-20090042876-A1 | Pyrroloquinoline Derivatives And Their Use As Protein Kinases Inhibitors | PIERRE FABRE MEDICAMENT (FR) | 2009-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042876-A1 | Pyrroloquinoline Derivatives And Their Use As Protein Kinases Inhibitors | MAP3K1, MAP3K2, MAP3K7 | CSNK2A2 114/4885CSNK2B 99/4885CSNK2A1 84/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.