Phosphoric Acid

Phosphoric Acid

SCHEMBL4172263

O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.O=P(O)(O)O.Oc1cc(O)c(O)c(O)c1O

nearest known ligand 0.43

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 known ✓ P27487 1/20 0.38
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 3/20 0.38
MAPT P10636 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
HPGD P15428 2/20 0.38
MAPK1 P28482 2/20 0.38
HSD17B10 Q99714 2/20 0.38
RECQL P46063 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MEN1 O00255 1/20 0.38
TTR P02766 1/20 0.38
CYP1A1 P04798 1/20 0.38
CYP3A4 P08684 1/20 0.38
HSPD1 P10809 1/20 0.38
ALOX15 P16050 1/20 0.38
ALOX12 P18054 1/20 0.38
MAOA P21397 1/20 0.38
ACHE P22303 1/20 0.38
MAOB P27338 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL4186931 1.00 KDM4E (0.38) KDM4EALDH1A1MAPTTDP1HPGD
SCHEMBL1961108 0.83 SELL (0.47) KDM4EALDH1A1MAPTTDP1HPGD
Phosphoric Acid SCHEMBL4181364 0.79 CA2 (0.39) KDM4ETDP1MAPK1HSD17B10CA2
Phosphoric Acid SCHEMBL27723050 0.79 CA2 (0.39) KDM4ETDP1MAPK1HSD17B10CA2
Phosphoric Acid SCHEMBL4191064 0.79 CA2 (0.39) KDM4ETDP1MAPK1HSD17B10CA2
SCHEMBL4186933 0.78 TDP1 (0.38) KDM4EALDH1A1MAPTTDP1HPGD
SCHEMBL4172265 0.78 TDP1 (0.38) KDM4EALDH1A1MAPTTDP1HPGD
Ethane SCHEMBL4867811 0.76 SELL (0.50) KDM4EALDH1A1MAPTTDP1HPGD
Gallic Acid SCHEMBL4875741 0.71 KDM4E (0.81) KDM4EALDH1A1MAPTTDP1HPGD
SCHEMBL14252038 0.71 CA2 (0.42) KDM4EALDH1A1MAPTTDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090098589-A1 Method DUPONT NUTRITION BIOSCIENCES APS (DK) 2009-04-16 US disclosed
EP-1888771-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2008-02-20 EP disclosed
WO-2006123254-A2 METHOD FOR DETERMINING PHYTASE ACTIVITY DANISCO A/S (DK) 2006-11-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090098589-A1 Method ALPL, PPA1, ITPA DPP4 307/4885KDM4E 2207/4885ALDH1A1 1801/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.