SCHEMBL4172854

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4172860	1.00	RAF1 (0.46)	RAF1TTRMAOBNR1H4S1PR5
	SCHEMBL4185994	0.83	RAF1 (0.44)	RAF1TTRMAOBNR1H4S1PR5
	SCHEMBL4185989	0.83	RAF1 (0.44)	RAF1TTRMAOBNR1H4S1PR5
	SCHEMBL4178568	0.76	RAF1 (0.42)	RAF1NR1H4POLBLMNAHPGD
	SCHEMBL4178572	0.76	RAF1 (0.42)	RAF1NR1H4POLBLMNAHPGD
	SCHEMBL4166783	0.73	RAF1 (0.40)	RAF1MAOBNR1H4S1PR5POLB
	SCHEMBL4166787	0.73	RAF1 (0.40)	RAF1MAOBNR1H4S1PR5POLB
	SCHEMBL10792354	0.73	PARP1 (0.60)	SMN1; SMN2
	SCHEMBL4172611	0.71	TAAR1 (0.41)	PLAU
	SCHEMBL4172616	0.71	TAAR1 (0.41)	PLAU

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.