SCHEMBL4185994

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4185989	1.00	RAF1 (0.44)	RAF1POLBTTRKMT2AMEN1
	SCHEMBL4178568	0.83	RAF1 (0.42)	RAF1POLBKMT2AMEN1ALDH1A1
	SCHEMBL4178572	0.83	RAF1 (0.42)	RAF1POLBKMT2AMEN1ALDH1A1
	SCHEMBL4172854	0.83	RAF1 (0.46)	RAF1POLBTTRNR1H4HPGD
	SCHEMBL4172860	0.83	RAF1 (0.46)	RAF1POLBTTRNR1H4HPGD
	SCHEMBL4411726	0.72	POLB (0.45)	RAF1POLBKMT2AMEN1ALDH1A1
	SCHEMBL4411730	0.72	POLB (0.45)	RAF1POLBKMT2AMEN1ALDH1A1
	SCHEMBL22982704	0.71	MAPT (0.58)	KMT2AMEN1ALDH1A1MAPTHPGD
	SCHEMBL16031988	0.71	TP53BP1 (0.46)	ALDH1A1MAPTERCC5FEN1
	SCHEMBL4422604	0.71	KMT2A (0.43)	RAF1POLBKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.