SCHEMBL4178568

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4178572	1.00	RAF1 (0.42)	RAF1DRD2NQO2HPGDLMNA
	SCHEMBL4185994	0.83	RAF1 (0.44)	RAF1HPGDGLAPOLBMEN1
	SCHEMBL4185989	0.83	RAF1 (0.44)	RAF1HPGDGLAPOLBMEN1
	SCHEMBL2166736	0.77	NQO2 (0.56)	NQO2HPGDGAAGLACA1
	SCHEMBL16079979	0.77	CTNNB1 (0.49)	NQO2HPGDGAAGLACA1
	SCHEMBL4183196	0.77	NR1H4 (0.38)	RAF1DRD2NQO2HPGDLMNA
	SCHEMBL4183191	0.77	NR1H4 (0.38)	RAF1DRD2NQO2HPGDLMNA
	SCHEMBL4172854	0.76	RAF1 (0.46)	RAF1HPGDLMNAPOLBNR1H4
	SCHEMBL4172860	0.76	RAF1 (0.46)	RAF1HPGDLMNAPOLBNR1H4
	SCHEMBL8803114	0.76	RARA (0.39)	NQO2HPGDLMNAGAAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.