Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.49 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 5/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.44 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acridone SCHEMBL345058 | 0.84 | ALDH1A1 (0.54) | DHODHESR1ESR2PDE10AMEN1 | |
| Acridone SCHEMBL429571 | 0.84 | ALDH1A1 (0.54) | DHODHESR1ESR2PDE10AMEN1 | |
| Acridone SCHEMBL243819 | 0.82 | KDM4E (0.56) | DHODHPDE10AMEN1KMT2AKDM4E | |
| Acridone SCHEMBL10800711 | 0.80 | KDM4E (0.54) | DHODHPDE10AMEN1KMT2AKDM4E | |
| Acridone SCHEMBL5719993 | 0.80 | KDM4E (0.54) | DHODHPDE10AMEN1KMT2AKDM4E | |
| Acridone SCHEMBL27574706 | 0.80 | KDM4E (0.54) | DHODHPDE10AMEN1KMT2AKDM4E | |
| SCHEMBL29274263 | 0.79 | ESR1 (0.68) | DHODHTRIM58MAP4K4ESR1ESR2 | |
| SCHEMBL30956249 | 0.79 | ESR1 (0.68) | DHODHTRIM58MAP4K4ESR1ESR2 | |
| SCHEMBL11060743 | 0.78 | KDM4E (0.67) | DHODHTRIM58MAP4K4ESR1ESR2 | |
| SCHEMBL9971889 | 0.76 | ALOX5 (0.54) | ESR1ESR2ALOX5BACE1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090096355-A1 | Aromatic Graft Polymer | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-04-16 | — | — | US | disclosed |
| EP-1892257-A1 | AROMATIC GRAFT POLYMER | Sumitomo Chemical Company, Limited (JP) | 2008-02-27 | — | — | EP | disclosed |